Microck

High-performance toolkit for genomic interval analysis in Rust with Python bindings. Use when working with genomic regions, BED files, coverage tracks, overlap detection, tokenization for ML models, or fragment analysis in computational genomics and machine learning applications.

Execute structured task plans with status tracking. Use when the user provides a plan file path in the format `plans/{current-date}-{task-name}-{version}.md` or explicitly asks you to execute a plan file.

Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats. This skill should be used when analyzing any scientific data file to understand its structure, content, quality, and characteristics. Automatically detects file type and generates detailed markdown reports with format-specific analysis, quality metrics, and downstream analysis recommendations. Covers

Create publication figures with matplotlib/seaborn/plotly. Multi-panel layouts, error bars, significance markers, colorblind-safe, export PDF/EPS/TIFF, for journal-ready scientific plots.

Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery: SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom parameters, use rdkit directly.

Generate detailed implementation plans for complex tasks. Creates comprehensive strategic plans in Markdown format with objectives, step-by-step implementation tasks using checkbox format, verification criteria, risk assessments, and alternative approaches. All plans MUST be validated using the included validation script. Use when users need thorough analysis and structured planning before impleme

Guide for maintaining the MassGen model and backend registry. This skill should be used when adding new models, updating model information (release dates, pricing, context windows), or ensuring the registry stays current with provider releases. Covers both the capabilities registry and the pricing/token manager.

Integrate new DEX aggregators, swappers, or bridge protocols (like Bebop, Portals, Jupiter, 0x, 1inch, etc.) into ShapeShift Web. Activates when user wants to add, integrate, or implement support for a new swapper. Guides through research, implementation, and testing following established patterns.

Master effective code review practices to provide constructive feedback, catch bugs early, and foster knowledge sharing while maintaining team morale. Use when reviewing pull requests, establishing review standards, or mentoring developers.

Use when managing multiple initiatives across time horizons (now/next/later, H1/H2/H3), balancing risk vs return across portfolio, sizing and sequencing bets with dependencies, setting exit/scale criteria for experiments, allocating resources across innovation types (core/adjacent/transformational), or when user mentions portfolio planning, roadmap horizons, betting framework, initiative prioritiz

Extracts and analyzes competitors' ads from ad libraries (Facebook, LinkedIn, etc.) to understand what messaging, problems, and creative approaches are working. Helps inspire and improve your own ad campaigns.

Execute Codex CLI for code analysis, refactoring, and automated code changes. Use when you need to delegate complex code tasks to Codex AI with file references (@syntax) and structured output.