Microck

Orchestrate complete PRP workflow from feature request to pull request. Run create branch, create PRP, execute implementation, commit changes, and create PR in sequence. Use when implementing features using PRP methodology or when user requests full PRP workflow.

Transform, clean, reshape, and preprocess data using pandas and numpy. Works with ANY LLM provider (GPT, Gemini, Claude, etc.).

Access USPTO APIs for patent/trademark searches, examination history (PEDS), assignments, citations, office actions, TSDR, for IP analysis and prior art searches.

This skill should be used when the user asks to "create a slash command", "add a command", "write a custom command", "define command arguments", "use command frontmatter", "organize commands", "create command with file references", "interactive command", "use AskUserQuestion in command", or needs guidance on slash command structure, YAML frontmatter fields, dynamic arguments, bash execution in com

Primary Python toolkit for molecular biology. Preferred for Python-based PubMed/NCBI queries (Bio.Entrez), sequence manipulation, file parsing (FASTA, GenBank, FASTQ, PDB), advanced BLAST workflows, structures, phylogenetics. For quick BLAST, use gget. For direct REST API, use pubmed-database.

Comprehensive GitHub project management with swarm-coordinated issue tracking, project board automation, and sprint planning

Downloads videos from YouTube and other platforms for offline viewing, editing, or archival. Handles various formats and quality options.

Generate production-quality TypeScript CLIs with full documentation, error handling, and best practices. Creates deterministic, type-safe command-line tools following PAI's CLI-First Architecture. USE WHEN user says "create a CLI", "build a command-line tool", "make a CLI for X", or requests CLI generation. (user)

Autonomous biomedical AI agent framework for executing complex research tasks across genomics, drug discovery, molecular biology, and clinical analysis. Use this skill when conducting multi-step biomedical research including CRISPR screening design, single-cell RNA-seq analysis, ADMET prediction, GWAS interpretation, rare disease diagnosis, or lab protocol optimization. Leverages LLM reasoning wit

Master effective code review practices to provide constructive feedback, catch bugs early, and foster knowledge sharing while maintaining team morale. Use when reviewing pull requests, establishing review standards, or mentoring developers.

Research libraries, APIs, and patterns using searchGitHub and Exa tools. Finds real-world implementations and saves structured reports to docs/research/. Use when investigating technologies, debugging issues, or comparing options.

Migrate prompts and code from Claude Sonnet 4.0, Sonnet 4.5, or Opus 4.1 to Opus 4.5. Use when the user wants to update their codebase, prompts, or API calls to use Opus 4.5. Handles model string updates and prompt adjustments for known Opus 4.5 behavioral differences. Does NOT migrate Haiku 4.5.