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View, query, and understand VCF/BCF variant files using bcftools and cyvcf2. Use when inspecting variants, extracting specific fields, or understanding VCF format structure.

Slice, extract, and concatenate biological sequences using Biopython. Use when extracting subsequences, joining sequences, or manipulating sequence regions by position.

Unified Python framework for extracellular electrophysiology. Load 20+ formats (SpikeGLX, OpenEphys, NWB, Intan, Maxwell, Blackrock), preprocess, run 10+ sorters (Kilosort4, SpykingCircus2, Tridesclous, MountainSort5) via one API, compute quality metrics (SNR, ISI, firing rate), compare sorters, export NWB/Phy. For format-agnostic multi-sorter workflows. For Neuropixels-specific PSTH/decoding use

Domine Python asyncio, programação concorrente e padrões async/await para aplicações de alto desempenho. Utilize ao construir APIs assíncronas, sistemas concorrentes ou aplicações com uso intensivo de I/O que exigem operações não bloqueantes.

Profile and optimize Python code using cProfile, memory profilers, and performance best practices. Use when debugging slow Python code, optimizing bottlenecks, or improving application performance.

Chunked N-D arrays for cloud storage. Compressed arrays, parallel I/O, S3/GCS integration, NumPy/Dask/Xarray compatible, for large-scale scientific computing pipelines.

Gera testes unitários automatizados para projetos Java (JUnit 5 + Mockito). Use quando o usuário solicitar a escrita de testes unitários, a geração de casos de teste ou o aumento da cobertura de teste.

Comprehensive guide for Firestore enterprise native including provisioning, data model, security rules, and SDK usage. Use this skill when the user needs help setting up Firestore Enterprise with the Native mode, writing security rules, or using the Firestore SDK in their application.

Automate Zoho CRM tasks via Rube MCP (Composio): create/update records, search contacts, manage leads, and convert leads. Always search tools first for current schemas.

飞书视频会议：让机器人代当前用户加入/离开正在进行的会议，并读取会议期间的实时事件（参会人加入与离开、发言、聊天、屏幕共享等）。1. 用户提供 9 位会议号、要求代为入会或离会时使用 +meeting-join / +meeting-leave——会真实产生入会/离会记录。2. 会议进行中用户想知道“谁加入了”“谁离开了”“谁在发言”“有人共享屏幕吗”等会中动态时，机器人入会后用 +meeting-events 读取事件时间线。3. 典型场景：参会机器人、会中助手、代为旁听、代为参会。前提：机器人只能读到它自己参会过且仍在进行中的会议的事件；查询已结束会议的参会名单、纪要或逐字稿请使用 lark-vc 技能。

Otimização de desempenho para React Native. Use ao otimizar listas, prevenir re-renderizações, memorizar componentes ou depurar problemas de desempenho em aplicativos Expo/React Native.

Universal coding standards, best practices, and patterns for TypeScript, JavaScript, React, and Node.js development.