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Variant calling with GATK HaplotypeCaller following best practices. Covers germline SNP/indel calling, GVCF workflow for cohorts, joint genotyping, and variant quality score recalibration (VQSR). Use when calling variants with GATK HaplotypeCaller.

Use when completing tasks, implementing major features, or before merging to verify work meets requirements.

Crie aplicativos de chat em tempo real com o SDK Java de Chat do Azure Communication Services. Use ao implementar threads de chat, mensagens, participantes, recibos de leitura, notificações de digitação ou recursos de chat em tempo real.

Use when facing 2+ independent tasks that can be worked on without shared state or sequential dependencies

Implement Kubernetes security policies including NetworkPolicy, PodSecurityPolicy, and RBAC for production-grade security. Use when securing Kubernetes clusters, implementing network isolation, or enforcing pod security standards.

gws CLI: Shared patterns for authentication, global flags, and output formatting.

Use when you have a spec or requirements for a multi-step task, before touching code

World-class ML engineering skill for productionizing ML models, MLOps, and building scalable ML systems. Expertise in PyTorch, TensorFlow, model deployment, feature stores, model monitoring, and ML infrastructure. Includes LLM integration, fine-tuning, RAG systems, and agentic AI. Use when deploying ML models, building ML platforms, implementing MLOps, or integrating LLMs into production systems.

Query the Cancer Dependency Map (DepMap) for cancer cell line gene dependency scores (CRISPR Chronos), drug sensitivity data, and gene effect profiles. Use for identifying cancer-specific vulnerabilities, synthetic lethal interactions, and validating oncology drug targets.

Guia para usar o Better Auth para autenticação do lado do cliente e do servidor.

Safely extend or refine AFI signal schemas and closely-related validators in afi-core, while preserving determinism, respecting PoI/PoInsight design, and obeying the AFI Droid Charter and AFI Core AGENTS.md boundaries.

A conceptual skill for integrating Better Auth with Next.js App Router