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Reconstruct ancestral sequences at phylogenetic nodes using PAML and IQ-TREE marginal likelihood methods. Infer ancient protein sequences and trace evolutionary trajectories through sequence history. Use when inferring ancestral states for protein resurrection or tracing evolutionary history.

Generates comprehensive, reviewer-friendly PR descriptions with visual diagrams, summary tables, collapsible sections, and structured test plans. Optimized for readability without sacrificing detail.

Esta skill ensina agentes a coletar e verificar evidências antes de marcar tarefas como concluídas. Inspirada em práticas de desenvolvimento de nível de produção, ela garante que todas as afirmações sejam apoiadas por provas executáveis.

Toolkit for styling artifacts with a theme. These artifacts can be slides, docs, reportings, HTML landing pages, etc. There are 10 pre-set themes with colors/fonts that you can apply to any artifact that has been creating, or can generate a new theme on-the-fly.

Structured approach to workplace conflicts, performance discussions, and challenging feedback using preparation-delivery-followup framework. Use when preparing for tough conversations, addressing conflicts, giving critical feedback, or navigating sensitive workplace discussions.

Process-based discrete-event simulation. Model queues, shared resources, timed events: manufacturing, service ops, network traffic, logistics. Processes are Python generators yielding events. Resources: capacity-limited (Resource/Priority/Preemptive), bulk (Container), objects (Store, FilterStore). For continuous use SciPy ODEs; for agent-based use Mesa.

Spreadsheet toolkit (.xlsx/.csv). Create/edit with formulas/formatting, analyze data, visualization, recalculate formulas, for spreadsheet processing and analysis.

Mark and remove PCR/optical duplicates using samtools fixmate and markdup. Use when preparing alignments for variant calling or when duplicate reads would bias analysis.

When the user wants to plan website structure, decide which pages to build, or prioritize pages for a new or existing site. Also use when the user mentions "website structure," "site structure," "which pages do I need," "page planning," "sitemap planning," "Must Have pages," "website architecture," or "site hierarchy." For a specific page template (e.g. homepage), use homepage-generator or landing

Add a new event type to the frontend feed system with corresponding React component. Use when user mentions "new event", "add event type", "event block", "new block type", or wants to display new agent output types.

Guide for annotating statistical significance (p-value asterisks) on comparison plots. Covers standard notation (ns, *, **, ***, ****), matplotlib bracket+asterisk implementation, and use with seaborn box/violin/bar plots. Use when preparing publication-ready figures with significance markers.

Transcription workflows, recording management, and quote extraction for journalists. Use when processing audio/video recordings, generating transcripts with timestamps, extracting quotes for fact-checking, or building source-and-recording databases. For interview question design and pre-interview preparation, see the interview-prep skill.