bg-szy

Normalize indel representation and split multiallelic variants using bcftools norm. Use when comparing variants from different callers or preparing VCF for downstream analysis.

Build Azure AI Foundry agents using the Microsoft Agent Framework Python SDK (agent-framework-azure-ai). Use when creating persistent agents with AzureAIAgentsProvider, using hosted tools (code interpreter, file search, web search), integrating MCP servers, managing conversation threads, or implementing streaming responses. Covers function tools, structured outputs, and multi-tool agents.

Active diagnostic tool for analyzing prompt quality, detecting anti-patterns, identifying token waste, and providing optimization recommendations

Use for Vue.js testing. Covers Vitest, Vue Test Utils, component testing, mocking, testing patterns, and Playwright for E2E testing.

Generate markdown documentation from Python codebases by analyzing source files, extracting docstrings, type hints, and code structure. Use when the user asks to document Python code, create API docs, or generate README files from source code.

Write modern C# code with advanced features like records, pattern

This skill should be used when the user asks to "add MCP server", "integrate MCP", "configure MCP in plugin", "use .mcp.json", "set up Model Context Protocol", "connect external service", mentions "${CLAUDE_PLUGIN_ROOT} with MCP", or discusses MCP server types (SSE, stdio, HTTP, WebSocket). Provides comprehensive guidance for integrating Model Context Protocol servers into Claude Code plugins for

Python type safety with type hints, generics, protocols, and strict type checking. Use when adding type annotations, implementing generic classes, defining structural interfaces, or configuring mypy/pyright.

Create publication-quality visualizations of immune repertoire data including circos plots, clone tracking, diversity plots, and network graphs. Use when generating figures for repertoire comparisons, clonal dynamics, or V(D)J gene usage.

Four-phase root cause investigation before attempting fixes. Use when debugging bugs, test failures, or unexpected behavior.

When the user wants to run CTV, OTT, or streaming TV ads. Also use when the user mentions "CTV ads," "connected TV," "OTT advertising," "streaming ads," "TV ads," "Hulu ads," "Roku ads," "YouTube TV ads," or "programmatic TV." For paid mix, use paid-ads-strategy.

Query Ensembl genome database REST API for 250+ species. Gene lookups, sequence retrieval, variant analysis, comparative genomics, orthologs, VEP predictions, for genomic research.