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TanStack Query + Zustand patterns.

Elite UX/UI & Advanced GSAP Motion Engineer. Enforces Python-driven true randomization for layout variance, strict AIDA page structure, wide editorial typography (bans 6-line wraps), gapless bento grids, strict GSAP ScrollTriggers (pinning, stacking, scrubbing), inline micro-images, and massive section spacing.

Execute the MAD-based single-cell RNA-seq QC workflow (scripts + Python API) to filter low-quality cells and emit reports plus filtered AnnData files.

Use when starting feature work that needs isolation from current workspace or before executing implementation plans - creates isolated git worktrees with smart directory selection and safety verification

Senior Laravel Engineer role for production-grade, maintainable, and idiomatic Laravel solutions. Focuses on clean architecture, security, performance, and modern standards (Laravel 10/11+).

Start the backend (FastAPI/uvicorn) and frontend (Vite) development servers. Use when user mentions "start dev", "run servers", "launch app", "start the app", or needs to run the application locally.

Turn the current conversation context into a PRD and publish it to the project issue tracker. Use when user wants to create a PRD from the current context.

Newsletter curation with content sourcing, editorial structure, and subscriber growth strategies. Covers issue formatting, link roundups, commentary style, and sending cadence. Use for: email newsletters, link roundups, weekly digests, curated content, creator newsletters. Triggers: newsletter, email newsletter, newsletter curation, weekly digest, link roundup, curated newsletter, newsletter writi

Google Sheets: Read values from a spreadsheet.

Add new HTTP endpoints to Catalyst-Relay server. Use when creating routes, API endpoints, or HTTP handlers.

Use when encountering any bug, test failure, or unexpected behavior, before proposing fixes. Four-phase framework ensuring understanding before attempting solutions.

Calls DNA methylation from Oxford Nanopore sequencing data using signal-level analysis. Use when detecting 5mC or 6mA modifications directly from nanopore reads without bisulfite conversion.