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Patterns and techniques for analyzing brownfield codebases. Use when onboarding to unfamiliar code, preparing for refactoring, conducting architecture reviews, or identifying technical debt.

Discover novel miRNAs and quantify known miRNAs using miRDeep2 de novo prediction from small RNA-seq data. Use when identifying new miRNAs or performing comprehensive miRNA profiling with discovery.

Web browser game development principles. Framework selection, WebGPU, optimization, PWA.

Annotate CLIP-seq peaks or crosslink sites to RNA features (5'UTR, CDS, 3'UTR, intron, splice junction, snoRNA, tRNA, ncRNA, repeat elements) with ChIPseeker, RCAS, RBP-Maps (Yeo splicing regulatory maps), and bedtools, applying feature-priority hierarchies, transcript-context resolution, and metagene aggregation. Use when characterizing where in transcripts an RBP binds, comparing peak distributi

Expo Router navigation patterns for React Native. Use when implementing navigation, routing, deep links, tab bars, modals, or handling navigation state in Expo apps.

AI-powered analysis of cellular senescence for aging research, cancer therapy response, and senolytic drug development.

Run after making React changes to catch issues early. Use when reviewing code, finishing a feature, or fixing bugs in a React project.

Call topologically associating domains (TADs) from Hi-C data using insulation score, HiCExplorer, and other methods. Identify domain boundaries and hierarchical domain structure. Use when calling TADs from Hi-C insulation scores.

Analyzes smart contract codebases to identify state-changing entry points for security auditing. Detects externally callable functions that modify state, categorizes them by access level (public, admin, role-restricted, contract-only), and generates structured audit reports. Excludes view/pure/read-only functions. Use when auditing smart contracts (Solidity, Vyper, Solana/Rust, Move, TON, CosmWasm

Orchestrates an end-to-end de novo genome assembly project, routing each step to the right genome-assembly skill rather than restating it. Profiles the genome first (k-mer spectrum -> size, heterozygosity, ploidy), QCs reads, chooses an assembly path by data type (SPAdes for Illumina, Flye for noisy long reads, hifiasm for HiFi, metaFlye for communities), polishes only when needed, decontaminates,

信号塔修复 - Stella尝试修复或建造信号发射装置,希望联系地球或发送求救信号

Detect common security vulnerabilities in code. Covers OWASP patterns, SQL injection, bare excepts, shell injection. Framework-agnostic.