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Realiza revisões de literatura abrangentes e sistemáticas em domínios biomédicos, científicos e técnicos, utilizando múltiplos bancos de dados acadêmicos (ex: PubMed, arXiv). Ideal para revisões sistemáticas, meta-análises e síntese de pesquisa, gerando documentos markdown e PDFs formatados profissionalmente.

WikiPathways enrichment using clusterProfiler and rWikiPathways. Use when analyzing gene lists against community-curated open-source pathways. Performs over-representation analysis and GSEA for 30+ species.

TypeScript and JavaScript expert with deep knowledge of type-level programming, performance optimization, monorepo management, migration strategies, and modern tooling. Use PROACTIVELY for any TypeScript/JavaScript issues including complex type gymnastics, build performance, debugging, and architectural decisions. If a specialized expert is a better fit, I will recommend switching and stop.

JACKS (Joint Analysis of CRISPR/Cas9 Knockout Screens) for modeling sgRNA efficacy and gene essentiality. Use when analyzing multiple CRISPR screens simultaneously or when accounting for variable sgRNA efficiency across experiments.

Applies ACMG/AMP 2015 framework with ClinGen SVI specifications, Tavtigian 2018/2020 Bayesian point system, Abou Tayoun 2018 PVS1 decision tree, Pejaver 2022 calibrated PP3/BP4 thresholds for REVEL/BayesDel/AlphaMissense, Brnich 2020 PS3/BS3 OddsPath, Walker 2023 SpliceAI splicing framework, and AMP/ASCO/CAP 2017 tumor tiers. Use when classifying germline variants P / LP / VUS / LB / B, applying V

Expert DevOps troubleshooter specializing in rapid incident

Analisa planilhas Excel, cria tabelas dinâmicas, gera gráficos e realiza análise de dados. Utilize ao analisar arquivos Excel, planilhas, dados tabulares ou arquivos .xlsx.

Auto-review pipeline — reads the full CEO, design, eng, and DX review skills from disk and runs them sequentially with auto-decisions using 6 decision principles. Surfaces taste decisions (close approaches, borderline scope, codex disagreements) at a final approval gate. One command, fully reviewed plan out. Use when asked to "auto review", "autoplan", "run all reviews", "review this plan automati

Search arXiv physics, math, and computer science preprints using natural language queries. Powered by Valyu semantic search.

Template for production-grade DocEngineering skills

Create portable, standards-based bioinformatics pipelines with Common Workflow Language (CWL). Use when building workflows that need maximum portability across execution platforms, sharing pipelines with collaborators using different systems, or contributing to community workflow registries.

When the user wants to optimize heading structure (H1-H6), fix heading hierarchy, or improve content structure. Also use when the user mentions "H1," "heading," "heading hierarchy," "content structure," "H2," "H3," "heading tags," "heading SEO," "multiple H1," or "heading structure." For SEO workflow, use seo-strategy.