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Guide for creating high-quality MCP (Model Context Protocol) servers that enable LLMs to interact with external services through well-designed tools. Use when building MCP servers to integrate external APIs or services, whether in Python (FastMCP) or Node/TypeScript (MCP SDK).

Crie componentes usando utilitários do Angular CDK, incluindo arrastar e soltar, sobreposição, portal, rolagem, acessibilidade, área de transferência e detecção de plataforma para o projeto ng-events.

Lab automation platform for Flex/OT-2 robots. Write Protocol API v2 protocols, liquid handling, hardware modules (heater-shaker, thermocycler), labware management, for automated pipetting workflows.

Orientação para instrumentar webapps com Azure Application Insights. Fornece padrões de telemetria, configuração do SDK e referências de configuração.

Create and manage Home Assistant YAML configuration files including automations, scripts, templates, blueprints, Lovelace dashboards, and file organization. Use when working with Home Assistant configuration files (.yaml, .yml) or discussing HA automations, scripts, sensors, or dashboards.

O SDK JavaScript/TypeScript do Azure File Share (@azure/storage-file-share) permite operações de compartilhamento de arquivos SMB, como criar compartilhamentos, gerenciar diretórios, fazer upload/download de arquivos e manipular metadados, suportando cenários de protocolo SMB do Azure Files.

Analyzes chemical libraries by scaffold using Bemis-Murcko scaffolds, generic frameworks, cyclic skeletons, matched molecular pair (MMP) analysis via mmpdb, R-group decomposition, Free-Wilson analysis, scaffold hopping, and chemotype-aware ML train/test splits. Use when identifying chemotype clusters in a library, deriving SAR transformation rules, decomposing series into R-groups, performing scaf

Code quality standards, linting rules, and CI/CD principles.

Compare GWAS studies, perform meta-analyses, and assess replication across cohorts. Integrates NHGRI-EBI GWAS Catalog and Open Targets Genetics to compare study designs, effect sizes, ancestry diversity, and heterogeneity statistics. Use when comparing GWAS studies for a trait, performing meta-analysis of genetic loci, assessing replication across cohorts, or exploring the genetic architecture of

Comprehensive geospatial science skill covering remote sensing, GIS, spatial analysis, machine learning for earth observation, and 30+ scientific domains. Supports satellite imagery processing (Sentinel, Landsat, MODIS, SAR, hyperspectral), vector and raster data operations, spatial statistics, point cloud processing, network analysis, cloud-native workflows (STAC, COG, Planetary Computer), and 8

Similarity Network Fusion (SNF) for patient stratification using multi-omics data. Integrates multiple data types into a unified patient similarity network. Use when performing patient stratification or integrating multi-omics data into unified similarity networks.

Release workflow for baoyu-skills plugin. Use when user says "release", "发布", "push", "推送", "new version", "新版本", "bump version", "更新版本", or wants to publish changes to remote. Analyzes changes since last tag, updates CHANGELOG (EN/CN), bumps marketplace.json version, commits, and creates version tag. MUST be used before any git push with uncommitted skill changes.