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End-to-end copy number variant detection workflow from BAM files. Covers CNVkit analysis for exome/targeted sequencing with visualization and annotation. Use when detecting copy number alterations from sequencing data.

Implement accessible user interfaces with semantic HTML, keyboard navigation, sufficient color contrast, screen reader support, ARIA attributes, and proper focus management. Use this skill when creating or editing React components (.tsx, .jsx files), when implementing forms with labels and inputs, when building interactive elements (buttons, modals, menus, dialogs), when implementing keyboard navi

API key for MaxHub data APIs. Get one at https://www.aconfig.cn

Meta-skill that analyzes the Trail of Bits Testing Handbook (appsec.guide) and generates Claude Code skills for security testing tools and techniques. Use when creating new skills based on handbook content.

Diagnose and fix Claude in Chrome MCP extension connectivity issues. Use when mcp__claude-in-chrome__* tools fail, return "Browser extension is not connected", or behave erratically.

Python library for working with DICOM (Digital Imaging and Communications in Medicine) files. Use this skill when reading, writing, or modifying medical imaging data in DICOM format, extracting pixel data from medical images (CT, MRI, X-ray, ultrasound), anonymizing DICOM files, working with DICOM metadata and tags, converting DICOM images to other formats, handling compressed DICOM data, or proce

Dockerfile security linting and best practice validation using Hadolint with 100+ built-in rules aligned to CIS Docker Benchmark. Use when: (1) Analyzing Dockerfiles for security misconfigurations and anti-patterns, (2) Enforcing container image security best practices in CI/CD pipelines, (3) Detecting hardcoded secrets and credentials in container builds, (4) Validating compliance with CIS Docker

Protocolo mestre para desconstruir frameworks de agentes, informando a arquitetura de sistemas derivados. É usado para análise abrangente, comparação de frameworks, design de novos sistemas, documentação de decisões ou due diligence técnica em implementações de agentes de IA.

Orquestre um fluxo de trabalho Git abrangente, desde a revisão de código até a criação de PRs, utilizando agentes especializados para garantia de qualidade, testes e prontidão para implantação. Este fluxo de trabalho implementa g moderno.

Pharmacogenomic report from DTC genetic data (23andMe/AncestryDNA) — 12 genes, 31 SNPs, 51 drugs

Cria automaticamente changelogs para usuários a partir de commits Git, analisando o histórico de commits, categorizando mudanças e transformando commits técnicos em notas de lançamento claras e amigáveis ao cliente. Transforma horas de escrita manual de changelogs em minutos de geração automatizada.

Apply professional typographic rules to screen-based UI. Use when generating any UI with visible text, auditing typography violations, or when the user asks about font sizing, line height, spacing, quotes, dashes, or text formatting in interfaces.