bg-szy

Query NCBI ClinVar via E-utilities for variant clinical significance, pathogenicity, disease associations. Search by gene/rsID/condition/review status; returns ClinSig, submitter data, conditions, HGVS. For GWAS use gwas-database; for variant consequence prediction use Ensembl VEP.

Expert in event sourcing, CQRS, and event-driven architecture patterns. Masters event store design, projection building, saga orchestration, and eventual consistency patterns. Use PROACTIVELY for event-sourced systems, audit trails, or temporal queries.

Generates and updates the latest app changelog based on git history since the last version tag.

Model Context Protocol (MCP) integration specialist. Use when creating

Use this skill whenever the user wants to create, read, edit, or manipulate Word documents (.docx files). Triggers include: any mention of 'Word doc', 'word document', '.docx', or requests to produce professional documents with formatting like tables of contents, headings, page numbers, or letterheads. Also use when extracting or reorganizing content from .docx files, inserting or replacing images

Analyze Perturb-seq and CROP-seq CRISPR screening data integrated with scRNA-seq. Use when identifying gene function through pooled genetic perturbations in single cells.

Create and manage Claude Code skills following Anthropic best practices. Use when creating new skills, modifying skill-rules.json, understanding trigger patterns, working with hooks, debugging skill activation, or implementing progressive disclosure. Covers skill structure, YAML frontmatter, trigger types (keywords, intent patterns, file paths, content patterns), enforcement levels (block, suggest

Comprehensive technology stack evaluation and comparison tool with TCO analysis, security assessment, and intelligent recommendations for engineering teams

Habilidade de design abrangente que inclui identidade de marca, tokens de design, estilo de UI, geração de logotipos (55 estilos com Gemini AI), programa de identidade corporativa (50 entregáveis), apresentações HTML, design de banners (22 estilos) e ícones (15 estilos, SVG).

Genome-wide association studies (GWAS) with PLINK. Perform case-control and quantitative trait association testing using logistic/linear regression with covariates, generate Manhattan and QQ plots for result visualization. Use when running GWAS or association tests.

Gera um esqueleto de repositório GitHub 'awesome-list' específico por tópico, completo com um README polido, regras de contribuição, instruções para agentes de IA, verificação de URL, licença e modelos reutilizáveis. Ideal para criar novos repositórios 'awesome', listas curadas ou catálogos de recursos por tópico a partir de um tópico e critérios opcionais.

Verify code quality standards are met - naming, structure, DRY principles. Issues result in SUGGESTIONS for improvement.