jackspace

Direct REST API access to PubMed. Advanced Boolean/MeSH queries, E-utilities API, batch processing, citation management. For Python workflows, prefer biopython (Bio.Entrez). Use this for direct HTTP/REST work or custom API implementations.

Query STRING API for protein-protein interactions (59M proteins, 20B interactions). Network analysis, GO/KEGG enrichment, interaction discovery, 5000+ species, for systems biology.

Access ZINC (230M+ purchasable compounds). Search by ZINC ID/SMILES, similarity searches, 3D-ready structures for docking, analog discovery, for virtual screening and drug discovery.

Benchling R&D platform integration. Access registry (DNA, proteins), inventory, ELN entries, workflows via API, build Benchling Apps, query Data Warehouse, for lab data management automation.

Latch platform for bioinformatics workflows. Build pipelines with Latch SDK, @workflow/@task decorators, deploy serverless workflows, LatchFile/LatchDir, Nextflow/Snakemake integration.

Lab automation platform for Flex/OT-2 robots. Write Protocol API v2 protocols, liquid handling, hardware modules (heater-shaker, thermocycler), labware management, for automated pipetting workflows.

Molecular machine learning toolkit. Property prediction (ADMET, toxicity), GNNs (GCN, MPNN), MoleculeNet benchmarks, pretrained models, featurization, for drug discovery ML.

Diffusion-based molecular docking. Predict protein-ligand binding poses from PDB/SMILES, confidence scores, virtual screening, for structure-based drug design. Not for affinity prediction.

This skill provides production-ready AI chat UI components built on shadcn/ui for conversational AI interfaces. Use when building ChatGPT-style chat interfaces with streaming responses, tool/function call displays, reasoning visualization, or source citations. Provides 30+ components including Message, Conversation, Response, CodeBlock, Reasoning, Tool, Actions, Sources optimized for Vercel AI SDK

Backend AI functionality with Vercel AI SDK v5 - text generation, structured output with Zod, tool calling, and agents. Multi-provider support for OpenAI, Anthropic, Google, and Cloudflare Workers AI. Use when: implementing server-side AI features, generating text/chat completions, creating structured AI outputs with Zod schemas, building AI agents with tools, streaming AI responses, integrating O

Comprehensive backend development guide for Node.js/Express/TypeScript microservices. Use when creating routes, controllers, services, repositories, middleware, or working with Express APIs, Prisma database access, Sentry error tracking, Zod validation, unifiedConfig, dependency injection, or async patterns. Covers layered architecture (routes → controllers → services → repositories), BaseControll

Use when creating or developing, before writing code or implementation plans - refines rough ideas into fully-formed designs through collaborative questioning, alternative exploration, and incremental validation. Don't use during clear 'mechanical' processes

Process and generate multimedia content using Google Gemini API. Capabilities include analyze audio files (transcription with timestamps, summarization, speech understanding, music/sound analysis up to 9.5 hours), understand images (captioning, object detection, OCR, visual Q&A, segmentation), process videos (scene detection, Q&A, temporal analysis, YouTube URLs, up to 6 hours), extract from docum

This skill provides project-specific coding conventions, architectural principles, repository structure standards, testing patterns, and contribution guidelines for the better-chatbot project (https://github.com/cgoinglove/better-chatbot). Use this skill when contributing to or working with better-chatbot to understand the design philosophy and ensure code follows established patterns. Includes: A

Creates complete single-file HTML/CSS/JS web apps with localStorage persistence, ADHD-optimized UI (60px+ buttons), dark mode, and offline functionality. Use when user says "create app", "build tool", "make dashboard", or requests any browser-based interface.

This skill provides comprehensive knowledge for working with the Anthropic Messages API (Claude API). It should be used when integrating Claude models into applications, implementing streaming responses, enabling prompt caching for cost savings, adding tool use (function calling), processing images with vision capabilities, or using extended thinking mode. Use when building chatbots, AI assistants

Expert Git workflow management for Claude Code sessions with branch naming conventions, push retry logic, conflict resolution, and PR automation specifically designed for AI-assisted development workflows.

Comprehensive guide for the Cloudflare Agents SDK - build AI-powered autonomous agents on Workers + Durable Objects. Use when: building AI agents, creating stateful agents with WebSockets, implementing chat agents with streaming, scheduling tasks with cron/delays, running asynchronous workflows, building RAG (Retrieval Augmented Generation) systems with Vectorize, creating MCP (Model Context Proto

Complete knowledge domain for Cloudflare Cron Triggers - scheduled execution of Workers using cron expressions for periodic tasks, maintenance jobs, and automated workflows. Use when: scheduling Workers to run periodically, adding cron triggers to Workers, configuring scheduled tasks, testing cron handlers, combining crons with Workflows, enabling Green Compute, handling multiple schedules, or enc

Complete knowledge domain for Cloudflare Queues - flexible message queue for asynchronous processing and background tasks on Cloudflare Workers. Use when: creating message queues, async processing, background jobs, batch processing, handling retries, configuring dead letter queues, implementing consumer concurrency, or encountering "queue timeout", "batch retry", "message lost", "throughput exceed

Frontend React hooks for AI-powered chat interfaces, completions, and streaming UIs with Vercel AI SDK v5. Includes useChat, useCompletion, and useObject hooks for building interactive AI applications. Use when: building React chat interfaces, implementing AI completions in UI, streaming AI responses to frontend, handling chat message state, building Next.js AI apps, managing file attachments with

Production-tested setup for AutoAnimate (@formkit/auto-animate) - a zero-config, drop-in animation library that automatically adds smooth transitions when DOM elements are added, removed, or moved. This skill should be used when building UIs that need simple, automatic animations for lists, accordions, toasts, or form validation messages without the complexity of full animation libraries. Use when

Implement authentication and authorization with Better Auth - a framework-agnostic TypeScript authentication framework. Features include email/password authentication with verification, OAuth providers (Google, GitHub, Discord, etc.), two-factor authentication (TOTP, SMS), passkeys/WebAuthn support, session management, role-based access control (RBAC), rate limiting, and database adapters. Use whe

从哔哩哔哩(B站)搜索视频、获取字幕并转换为 Markdown 格式。当用户需要搜索 B 站视频、下载视频字幕、批量获取字幕、分析视频内容时使用。支持关键词搜索、单视频处理、批量并发下载。

Creating interactive data visualisations using d3.js. This skill should be used when creating custom charts, graphs, network diagrams, geographic visualisations, or any complex SVG-based data visualisation that requires fine-grained control over visual elements, transitions, or interactions. Use this for bespoke visualisations beyond standard charting libraries, whether in React, Vue, Svelte, vani

This skill provides comprehensive knowledge for Cloudflare Images, covering both the Images API (upload/storage) and Image Transformations (optimize any image). It should be used when uploading images to Cloudflare, resizing images, optimizing image delivery, implementing direct creator uploads, creating image variants, generating signed URLs for private images, transforming images via Workers, or

Generates production-ready API clients with TypeScript types, retry logic, rate limiting, authentication (OAuth, API keys), error handling, and mock responses. Use when user says "integrate API", "API client", "connect to service", or requests third-party service integration.

Production-tested setup for Base UI (@base-ui-components/react) - MUI's unstyled component library that provides accessible, customizable React components using render props pattern. This skill should be used when building accessible UIs with full styling control, migrating from Radix UI, or needing components with Floating UI integration for smart positioning. Use when: Setting up Base UI in Vite

Browser automation, debugging, and performance analysis using Puppeteer CLI scripts. Use for automating browsers, taking screenshots, analyzing performance, monitoring network traffic, web scraping, form automation, and JavaScript debugging.

ClaudeSkillz: For when you need skills, but lazier

Complete knowledge domain for Cloudflare Browser Rendering - Headless Chrome automation with Puppeteer and Playwright on Cloudflare Workers for screenshots, PDFs, web scraping, and browser automation workflows. Use when: taking screenshots, generating PDFs from HTML or URLs, web scraping content, crawling websites, browser automation tasks, testing web applications, managing browser sessions, perf

Complete knowledge domain for Cloudflare D1 - serverless SQLite database on Cloudflare's edge network. Use when: creating D1 databases, writing SQL migrations, configuring D1 bindings, querying D1 from Workers, handling SQLite data, building relational data models, or encountering "D1_ERROR", "statement too long", "too many requests queued", migration failures, or query performance issues. Keyword

Comprehensive guide for Cloudflare Durable Objects - globally unique, stateful objects for coordination, real-time communication, and persistent state management. Use when: building real-time applications, creating WebSocket servers with hibernation, implementing chat rooms or multiplayer games, coordinating between multiple clients, managing per-user or per-room state, implementing rate limiting

Complete guide for Cloudflare Email Routing covering both Email Workers (receiving emails) and Send Email bindings (sending emails from Workers). Use when: setting up email routing, creating email workers, processing incoming emails, sending emails from Workers, implementing email allowlists/blocklists, forwarding emails with custom logic, replying to emails automatically, parsing email content, c

Production-ready Auth.js v5 setup for Next.js and Cloudflare Workers. Use when: setting up authentication, implementing OAuth/credentials/magic links, configuring D1 or PostgreSQL adapters, debugging session issues, migrating from v4 to v5, fixing edge compatibility, troubleshooting JWT/database sessions, resolving AUTH_SECRET errors, fixing CallbackRouteError, or implementing RBAC. Covers: Next.j

Expert helper for bash scripting, debugging, and best practices

Production-ready authentication framework for TypeScript with first-class Cloudflare D1 support. Use this skill when building auth systems as a self-hosted alternative to Clerk or Auth.js, particularly for Cloudflare Workers projects. Supports social providers (Google, GitHub, Microsoft, Apple), email/password, magic links, 2FA, passkeys, organizations, and RBAC. Prevents 10+ common authentication

This skill provides reusable implementation patterns extracted from the better-chatbot project for custom AI chatbot deployments. Use this skill when building AI chatbots with server action validators, tool abstraction systems, workflow execution, or multi-AI provider integration in your own projects (not contributing to better-chatbot itself). Use when: building AI chatbot features, implementing

ClaudeSkillz: For when you need skills, but lazier

Build resumable state-machine workflows with checkpoint patterns, progress preservation, and automatic recovery for complex multi-phase operations that need to survive interruptions, timeouts, and failures.

This skill provides comprehensive knowledge for working with the Anthropic Claude Agent SDK. It should be used when building autonomous AI agents, creating multi-step reasoning workflows, orchestrating specialized subagents, integrating custom tools and MCP servers, or implementing production-ready agentic systems with Claude Code's capabilities. Use when building coding agents, SRE systems, secur

Add interaction states like hover, focus, disabled, active, error to existing uxscii components. Use when working with .uxm files, when user wants to expand, enhance, or add states to .uxm components.

Comprehensive knowledge for using the Bash tool in Claude Code effectively. This skill should be used when orchestrating CLI tools, configuring hooks, setting up automation workflows, managing git operations, handling multi-command patterns, or encountering Bash tool errors. Covers: PreToolUse hooks, command chaining patterns, git workflow automation, CLI tool integration, custom commands (.claude

This skill provides comprehensive knowledge for integrating Clerk authentication in React, Next.js, and Cloudflare Workers applications. It should be used when setting up user authentication, implementing protected routes, verifying JWT tokens, creating custom JWT templates with user metadata and organization claims, configuring Clerk middleware, integrating with shadcn/ui components, testing auth

Production-tested integration patterns for connecting React frontends to Cloudflare Worker backends with Hono, Clerk authentication, and D1 databases. Prevents common frontend-backend connection issues, CORS errors, auth token failures, and race conditions. Use when: connecting frontend to backend, implementing auth flow, setting up API calls, troubleshooting CORS, fixing race conditions, auth tok

Complete knowledge domain for Cloudflare Hyperdrive - connecting Cloudflare Workers to existing PostgreSQL and MySQL databases with global connection pooling, query caching, and reduced latency. Use when: connecting Workers to existing databases, migrating PostgreSQL/MySQL to Cloudflare, setting up connection pooling, configuring Hyperdrive bindings, using node-postgres/postgres.js/mysql2 drivers,

Complete knowledge domain for Cloudflare Workers KV - global, low-latency key-value storage on Cloudflare's edge network. Use when: creating KV namespaces, storing configuration data, caching API responses, managing user preferences, implementing TTL expiration, handling KV metadata, or encountering "KV_ERROR", "429 too many requests", "kv rate limit", cacheTtl errors, or eventual consistency issu

This skill provides comprehensive knowledge for implementing Cloudflare Turnstile, the CAPTCHA-alternative bot protection system. It should be used when integrating bot protection into forms, login pages, signup flows, or any user-facing feature requiring spam/bot prevention. Turnstile runs invisible challenges in the background, maintaining excellent user experience while blocking automated traff