bio-causal-genomics-pleiotropy-detection

Name: bio-causal-genomics-pleiotropy-detection
Rating: 5 (1 reviews)
Author: bg-szy

Detect and correct for horizontal pleiotropy in Mendelian randomization analyses using MR-PRESSO for outlier removal, MR-Egger regression for directional pleiotropy, and Steiger filtering for variant directionality. Use when validating MR results, detecting pleiotropic instruments, or running sensitivity analyses for causal inference.

1stars

Updated 18 days ago

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Version Compatibility

Reference examples tested with: MR-PRESSO 1.0+, TwoSampleMR 0.5+

Before using code patterns, verify installed versions match. If versions differ:

R: packageVersion("<pkg>") then ?function_name to verify parameters

If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying.

Pleiotropy Detection

"Check my MR results for pleiotropic bias" → Detect and correct

[Description truncada. Veja o README completo no GitHub.]

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