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polars-bio
High-performance genomic interval operations and bioinformatics file I/O on Polars DataFrames. It supports overlap, nearest, merge, coverage, complement, and subtract for BED/VCF/BAM/GFF intervals, offering a streaming, cloud-native, and faster bioframe alternative.
rowan
Rowan is a cloud-native molecular modeling and medicinal-chemistry workflow platform with a Python API.
scientific-critical-thinking
This skill evaluates scientific claims and evidence quality, useful for assessing experimental design, identifying biases, and applying evidence grading frameworks. It's ideal for understanding evidence quality and identifying flaws, but not for formal peer review writing.
zarr-python
Zarr-Python 3 provides chunked N-D arrays for cloud storage, featuring compressed arrays, parallel I/O, S3/GCS compatibility via fsspec, and integration with NumPy/Dask/Xarray for large-scale scientific computing pipelines.
esm
A comprehensive toolkit for EvolutionaryScale protein language models, including ESM3 for generative multimodal design and ESM C for efficient embeddings. It supports various protein tasks like sequence/structure/function analysis, inverse folding, variant design, and ESMFold2 structure prediction, with local open weights and cloud support.
baoyu-cover-image
Generates article cover images with 5 dimensions (type, palette, rendering, text, mood), combining 11 color palettes and 7 rendering styles. It supports cinematic (2.35:1), widescreen (16:9), and square (1:1) aspects. Use when the user asks to generate a cover image, create an article cover, or make a cover.
baoyu-markdown-to-html
Converts Markdown to styled HTML with WeChat-compatible themes. It supports code highlighting, math, Mermaid, PlantUML, footnotes, alerts, infographics, and optional bottom citations for external links.
baoyu-post-to-x
Posts content and articles to X (Twitter), including regular posts with images/videos and long-form X Articles in Markdown. Use this skill when asked to 'post to X', 'tweet', or 'publish to Twitter'.
baoyu-url-to-markdown
Fetches any URL and converts it to markdown using the baoyu-fetch CLI, which includes adapters for sites like X/Twitter and YouTube. It handles login/CAPTCHA, making it ideal for saving webpages as markdown.
azure-cloud-architect
Designs Azure architectures for startups and enterprises, covering infrastructure design, Bicep/ARM templates, cost optimization, Azure DevOps pipelines, and migration. Includes AKS, App Service, Azure Functions, and Cosmos DB.
cdo-review
/cs:cdo-review <plan> — Decision-driven Chief Data Officer interrogation of any plan that touches training data, data architecture, data productization, or data team hiring.
vpe-advisor
Advisory for VP of Engineering in startups, focusing on optimizing delivery throughput, hiring funnel, team structure, and production discipline.