Explore skills

Create and use BAI/CSI indices for BAM/CRAM files using samtools and pysam. Use when enabling random access to alignment files or fetching specific genomic regions.

Guide for implementing Grafana Loki - a horizontally scalable, highly available log aggregation system. Use when configuring Loki deployments, setting up storage backends (S3, Azure Blob, GCS), writing LogQL queries, configuring retention and compaction, deploying via Helm, integrating with OpenTelemetry, or troubleshooting Loki issues on Kubernetes.

Resolve the architecture of focal oncogene amplifications — extrachromosomal DNA (ecDNA), breakage-fusion-bridge (BFB) cycles, homogeneously staining regions (HSR), and linear amplification — from whole-genome sequencing with AmpliconArchitect, the AmpliconSuite pipeline, and AmpliconClassifier. Covers copy-number seed selection, breakpoint-graph reconstruction, balanced-flow optimization, ecDNA c

Runs external LLM code reviews (OpenAI Codex or Google Gemini CLI) on uncommitted changes, branch diffs, or specific commits. Use when the user asks for a second opinion, external review, codex review, gemini review, or mentions /second-opinion.

This skill should be used when deploying a Docusaurus site to GitHub Pages. It automates the configuration, building, and deployment process, handling GitHub Pages setup, environment configuration, and CI/CD automation, and includes local validation before GitHub Actions triggering.

Use when facing 2+ independent tasks that can be worked on without shared state or sequential dependencies

Get current weather conditions for a location. Use this skill when users ask about weather, temperature, current conditions, forecasts, or any weather-related queries like "What's the weather?", "Is it raining?", "How hot is it outside?", "What's the temperature?", or "Should I bring an umbrella?". Supports automatic location detection via IP or specific location queries.

Cloudflare Workers CLI for deploying, developing, and managing Workers, KV, R2, D1, Vectorize, Hyperdrive, Workers AI, Containers, Queues, Workflows, Pipelines, and Secrets Store. Load before running wrangler commands to ensure correct syntax and best practices.

Generate consensus FASTA sequences by applying VCF variants to a reference using bcftools consensus. Use when creating sample-specific reference sequences or reconstructing haplotypes.

A comprehensive performance specialist focused on analysis and optimization.

Searches molecular libraries for substructure matches using SMARTS patterns with RDKit. Filters compounds by pharmacophore features, functional groups, or scaffold matches with atom mapping. Use when finding compounds containing specific chemical moieties or filtering libraries by structural features.

Python scripting with uv and PEP 723 inline dependencies. Use when creating