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IBM quantum computing framework. Use when targeting IBM Quantum hardware, working with Qiskit Runtime for production workloads, or needing IBM optimization tools. Best for IBM hardware execution, quantum error mitigation, and enterprise quantum computing. For Google hardware use cirq; for gradient-based quantum ML use pennylane; for open quantum system simulations use qutip.

Codified expertise for returns authorization, receipt and inspection, disposition decisions, refund processing, fraud detection, and warranty claims management. Informed by returns operations managers with 15+ years experience. Includes grading frameworks, disposition economics, fraud pattern recognition, and vendor recovery processes. Use when handling product returns, reverse logistics, refund d

Configure human-in-the-loop gating for AI agent review actions in Claude Code. Use when setting up a project where an agent may post PR reviews, comments, merges, or edit CI configuration, and you want a cryptographically auditable approval trail with Cedar-enforced gates.

Compute the bacterial pan-genome from Prokka/Bakta GFF3 annotations with Roary's CD-HIT + BLAST + MCL clustering pipeline. Builds gene presence/absence matrices, core/soft-core/shell/cloud partitions, multi-FASTA core gene alignments (with `-e`), and a pan-genome reference. Use Panaroo for higher-accuracy pan-genomes from highly fragmented assemblies, PIRATE for paralog-aware clustering, or PPanGG

Cloud quantum chemistry platform with Python SDK. Run geometry optimization, conformer generation, torsional scans, and energy minimization (DFT/semiempirical), and retrieve properties (dipole, partial charges, frontier orbitals) — no local QC software or HPC needed.

Unified agent for leveraging single-cell foundation models (scGPT, scBERT, Geneformer, scFoundation) for cross-species annotation, perturbation prediction, and gene network inference.

Python library for biology: sequence manipulation (DNA/RNA/protein), pairwise/multiple alignment, phylogenetic trees (NJ, UPGMA), diversity (Shannon, Faith PD, Bray-Curtis, UniFrac), ordination (PCoA, CCA, RDA), stats (PERMANOVA, ANOSIM, Mantel), file I/O (FASTA, FASTQ, Newick, BIOM). Use for microbiome, community ecology, or phylogenetics.

Implement secure secrets management for CI/CD pipelines using Vault, AWS Secrets Manager, or native platform solutions. Use when handling sensitive credentials, rotating secrets, or securing CI/CD environments.

Step-by-step cookbook for setting up cryptographically signed audit trails on Claude Code tool calls. Use when explaining, evaluating, or demonstrating the pattern before committing to the protect-mcp runtime hooks. Covers Cedar policy, Ed25519 receipts, offline verification, tamper detection, CI/CD integration, and SLSA composition.

Process-based discrete-event simulation. Model queues, shared resources, timed events: manufacturing, service ops, network traffic, logistics. Processes are Python generators yielding events. Resources: capacity-limited (Resource/Priority/Preemptive), bulk (Container), objects (Store, FilterStore). For continuous use SciPy ODEs; for agent-based use Mesa.

Python-based workflow manager for reproducible, scalable pipelines. Define rules with file-based dependencies; Snakemake resolves execution order and parallelism. Runs local, SLURM, LSF, AWS, GCP via profiles; per-rule conda/Singularity envs. For NGS pipelines, ML training, and multi-step file processing. Use Nextflow for Groovy dataflow or nf-core integration.

Track, calculate, and optimize key performance metrics for SaaS, marketplace, consumer, and B2B startups from seed through Series A, including unit economics, growth efficiency, and cash management. Use this skill when defining a metrics framework, calculating CAC/LTV/burn multiple, benchmarking business health, or preparing metrics dashboards for investors or board reporting.