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Cloud quantum chemistry platform with Python SDK. Run geometry optimization, conformer generation, torsional scans, and energy minimization (DFT/semiempirical), and retrieve properties (dipole, partial charges, frontier orbitals) — no local QC software or HPC needed.

Python library for biology: sequence manipulation (DNA/RNA/protein), pairwise/multiple alignment, phylogenetic trees (NJ, UPGMA), diversity (Shannon, Faith PD, Bray-Curtis, UniFrac), ordination (PCoA, CCA, RDA), stats (PERMANOVA, ANOSIM, Mantel), file I/O (FASTA, FASTQ, Newick, BIOM). Use for microbiome, community ecology, or phylogenetics.

Step-by-step cookbook for setting up cryptographically signed audit trails on Claude Code tool calls. Use when explaining, evaluating, or demonstrating the pattern before committing to the protect-mcp runtime hooks. Covers Cedar policy, Ed25519 receipts, offline verification, tamper detection, CI/CD integration, and SLSA composition.

Process-based discrete-event simulation. Model queues, shared resources, timed events: manufacturing, service ops, network traffic, logistics. Processes are Python generators yielding events. Resources: capacity-limited (Resource/Priority/Preemptive), bulk (Container), objects (Store, FilterStore). For continuous use SciPy ODEs; for agent-based use Mesa.

Track, calculate, and optimize key performance metrics for SaaS, marketplace, consumer, and B2B startups from seed through Series A, including unit economics, growth efficiency, and cash management. Use this skill when defining a metrics framework, calculating CAC/LTV/burn multiple, benchmarking business health, or preparing metrics dashboards for investors or board reporting.

Use when you need exact symbolic math in Python — algebra, calculus, equation solving, symbolic linear algebra, or code generation via lambdify/LaTeX. Prefer NumPy or SciPy when floating-point approximations are sufficient.

Train and deploy neural networks in distributed E2B sandboxes with Flow Nexus

Structured messaging protocols for agent team communication including message type selection, plan approval, shutdown procedures, and anti-patterns to avoid. Use this skill when establishing communication norms for a newly spawned team, when deciding whether to send a direct message or a broadcast, when a team-lead needs to review and approve an implementer's plan before work begins, when orchestr

Offers the user an informed choice about how much response depth to consume before answering. Use this skill when the user explicitly wants to control response length, depth, or token budget. TRIGGER when: \"token budget\", \"token count\", \"token usage\", \"token limit\", \"response length\", \"answer depth\", \"short version\", \"brief answer\", \"detailed answer\", \"exhaustive answer\", \"res

Comprehensive antibody engineering and optimization for therapeutic development. Covers humanization, affinity maturation, developability assessment, and immunogenicity prediction. Use when asked to optimize antibodies, humanize sequences, or engineer therapeutic antibodies from lead to clinical candidate.

Identify and prioritize causal variants at GWAS loci using statistical fine-mapping and locus-to-gene predictions. Computes posterior probabilities for causal variants, links variants to genes via L2G predictions, annotates functional consequences, and suggests validation strategies. Use when asked to fine-map GWAS loci, prioritize causal variants, identify credible sets, or link GWAS signals to c

Provide actionable treatment recommendations for cancer patients based on molecular profile. Interprets tumor mutations, identifies FDA-approved therapies, finds resistance mechanisms, matches clinical trials. Use when oncologist asks about treatment options for specific mutations (EGFR, KRAS, BRAF, etc.), therapy resistance, or clinical trial eligibility.