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All-in-one FASTQ QC and adapter trimming. Auto-detects Illumina adapters, filters low-quality reads, corrects paired-end overlaps, emits HTML+JSON QC in one pass. 3-10x faster than Trim Galore/Trimmomatic. First step before STAR, BWA-MEM2, or Salmon.

Counts RNA-seq reads overlapping GTF gene features. Takes sorted STAR BAMs plus GTF; outputs a per-gene tab-delimited matrix across samples. Handles strandedness (0/1/2), paired-end, multi-sample batch counting in one command, and outputs assignment statistics. Use Salmon for alignment-free quantification; use featureCounts when STAR BAMs already exist.

Poisson-model peak caller for ChIP-seq/ATAC-seq BAMs. MACS3 callpeak finds enriched regions (TF sites or histone marks) vs input/IgG; outputs BED narrowPeak/broadPeak for motif analysis, annotation, and differential binding. Use narrow peaks for TF ChIP-seq and ATAC-seq; broad for H3K27me3, H3K9me3, and other broad marks.

全球最大的 Claude Code 技能聚合库 · 收录 3900+ 来自 12+ 来源的技能，提供在线搜索与趋势分析看板 / The world's largest Claude Code skill aggregation hub — 3900+ skills from 12+ sources with online search and trend dashboard

Read/write SAM/BAM/CRAM, VCF/BCF, FASTA/FASTQ. Region queries, pileup, variant filtering, read groups. Python htslib wrapper exposing samtools/bcftools CLI. Use STAR/BWA for alignment; GATK/DeepVariant for variant calling.

Scaffold, validate, preview, and manage Power BI PBIR report projects using pbi-cli. Invoke this skill whenever the user mentions "create report", "new report", "PBIR", "scaffold", "validate report", "report structure", "preview report", "report info", "reload Desktop", "convert report", ".pbip project", "report project", or wants to understand the PBIR folder format, set up a new report from scra

Generate personalized cold email sequences (7-14 emails) with A/B test subject lines, follow-up timing recommendations, and integrated social proof. Creates multi-touch campaigns optimized for response rates. Use when users need outbound email campaigns, sales sequences, or lead generation emails.

Write B2B cold emails and follow-up sequences that get replies. Use when the user wants to write cold outreach emails, prospecting emails, cold email campaigns, sales development emails, or SDR emails. Also use when the user mentions "cold outreach," "prospecting email," "outbound email," "email to leads," "reach out to prospects," "sales email," "follow-up email sequence," "nobody's replying to m

This skill provides the UOR ring algebra foundation for 0xagentprivacy, activating when discussing Z/(2^6)Z structure, its five operations (neg, bnot, xor, and, or), the identity neg(bnot(x))=succ(x), stratum as popcount, Pascal's row distribution, or the lattice's lack of dead ends.

This skill provides a full email workflow, including syncing emails via Himalaya CLI, browsing threads, reading messages, drafting replies, sending via SMTP, and archiving threads. It triggers on various email-related commands or user actions like replying or handling support.

Strategic 90-day GEO roadmap. Combines findings from technical, content, schema, and presence audits with the user's stated existing footprint to produce a sequenced plan: week-by-week actions, owners, expected score deltas, and verification checkpoints. Includes both technical fixes (robots.txt, schema, content rewrites) and creative work (Reddit cadence, Wikipedia draft, G2 review campaign, YouT

Verify real brand mentions in AI engine answers. Runs a curated set of category intent queries against ChatGPT, Claude, Perplexity, and Google AI Overviews (or their WebSearch proxies) and reports whether the brand appears in answers, whether the description is correct, and whether the sentiment is positive/neutral/negative. This is the only Pillar 5 ground truth — everything else is signal proxyi