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Perform AI-powered web searches with real-time information using Perplexity models via LiteLLM and OpenRouter. This skill should be used when conducting web searches for current information, finding recent scientific literature, getting grounded answers with source citations, or accessing information beyond the model's knowledge cutoff. Provides access to multiple Perplexity models including Sonar

Generate LESSONS.md retrospective files that capture institutional knowledge, especially failures. Use when closing out journalism projects, investigations, events, or publications. Includes templates for research projects, event post-mortems, editorial tools, and publications.

GWAS and population genetics tool. Processes PLINK (.bed/.bim/.fam), VCF, and BGEN; runs QC (MAF, HWE, missingness), IBD estimation, PCA, and linear/logistic regression GWAS. Outputs Manhattan-ready summary stats. Use regenie or SAIGE for biobanks (>100k samples) needing mixed models.

Prior Auth Review

Search PubMed for scientific literature. Use when the user asks to find papers, search literature, look up research, find publications, or asks about recent studies. Triggers on "pubmed", "papers", "literature", "publications", "research on", "studies about".

Geometric deep learning-based polygenic risk score prediction using PRS-Net for modeling gene interactions, enhanced disease prediction, and cross-ancestry portability.

Bayesian modeling with PyMC 5: priors, likelihood, NUTS/ADVI sampling, diagnostics (R-hat, ESS), LOO/WAIC comparison, prediction. Hierarchical, logistic, GP variants; predictive checks.

Create distributable Python packages with proper project structure, setup.py/pyproject.toml, and publishing to PyPI. Use when packaging Python libraries, creating CLI tools, or distributing Python code.

Python background job patterns including task queues, workers, and event-driven architecture. Use when implementing async task processing, job queues, long-running operations, or decoupling work from request/response cycles.

Python data processing pipelines with modular architecture. Use when building content processing workflows, implementing dispatcher patterns, integrating Google Sheets/Drive APIs, or creating batch processing systems. Covers patterns from rosen-scraper, image-analyzer, and social-scraper projects.

Python type safety with type hints, generics, protocols, and strict type checking. Use when adding type annotations, implementing generic classes, defining structural interfaces, or configuring mypy/pyright.

RFC-driven multi-agent DAG execution pattern with quality gates, merge queues, and work unit orchestration.