AlphaFold Predictor Skill
Purpose
Enable AlphaFold protein structure prediction with confidence assessment and model analysis.
Capabilities
- Structure prediction execution
- pLDDT confidence scoring
- PAE analysis
- Multi-chain complex prediction
- Template-based refinement
- ColabFold integration
Usage Guidelines
- Review pLDDT scores for prediction confidence
- Analyze PAE for domain boundaries
- Predict complexes for multi-protein assemblies
- Use templates when homologs exist
- Validate predictions against experimental data
- Document model versions and parameters
Dependencies
- AlphaFold2
- ColabFold
- RoseTTAFold
Process Integration
- Protein Structure Prediction (protein-structure-prediction)
- Molecular Docking and Virtual Screening (molecular-docking)