Arboreto GRN Inference
Overview
Arboreto infers gene regulatory networks (GRNs) from gene expression data using parallelized tree-based regression. For each target gene, it trains a regression model with all other genes (or a specified TF list) as features and emits TF-target-importance triplets. It provides two interchangeable algorithms -- GRNBoost2 (gradient boosting, fast) and GENIE3 (Random Forest, classic) -- sharing identical input/output formats. Computation is Dask-parallelized,
[Description truncada. Veja o README completo no GitHub.]