Format Quick Reference
| Format | Content | Coord system | Random access | Tools |
|---|---|---|---|---|
| FASTA | Sequences | N/A | With .fai index | samtools faidx, BioPython |
| FASTQ | Reads + quality | N/A | No (stream) | fastp, cutadapt |
| SAM | Alignments (text) | 1-based | No | samtools, awk |
| BAM | Alignments (binary) | 1-based | With .bai | samtools, pysam |
| CRAM | Alignments (ref-compressed) | 1-based | With .crai | samtools, htslib |
| VCF |
[Description truncada. Veja o README completo no GitHub.]