Functional Annotation of Metagenomes
References: HUMAnN3 · bioBakery · MetaCyc
HUMAnN3 Overview
Three-stage workflow:
- MetaPhlAn4 taxonomic profiling — identifies species and abundances; selects pangenome DBs for step 2.
- Pangenome alignment (Bowtie2) — aligns reads against nucleotide pangenomes of detected species.
- Unaligned read translation search (DIAMOND) —
[Description truncada. Veja o README completo no GitHub.]