Promoter and Regulatory Sequence Analysis
Key Regulatory Elements
| Element | Location | Function |
|---|---|---|
| Promoter | −1 to −1000 bp from TSS | Recruits RNA Pol II |
| Enhancer | Distal (kb–Mb away) | Boosts transcription |
| Silencer | Variable | Represses transcription |
| Insulator | Between elements | Blocks enhancer–promoter crosstalk |
- TSS = position +1; upstream = negative coordinates
- TATA box: consensus TATAAA at ~−30; present in ~10–20% o
[Description truncada. Veja o README completo no GitHub.]