Single-Cell ATAC-seq: Chromatin Accessibility
References: Signac | ArchR | chromVAR
scATAC-seq measures chromatin accessibility at single-cell resolution — direct readout of where TFs bind and regulatory decisions are made, upstream of expression changes.
Technology
Tn5 tagmentation: Hyperactive Tn5 inserts into nucleosome-free (accessible) regions, fragmenting DNA and
[Description truncada. Veja o README completo no GitHub.]