WGBS/RRBS Processing with Bismark
References: Bismark docs | methylKit vignette | ENCODE WGBS pipeline
DNA Methylation Biology
5mC added by DNMT3A/3B (de novo) and DNMT1 (maintenance). Removed by TET1/2/3 via 5hmC oxidation. Methylation occurs almost exclusively at CpG dinucleotides in mammals (~70–80% methylated).
| Feature | M
[Description truncada. Veja o README completo no GitHub.]