Hi-C Analysis: 3D Genome Organization
- Load and inspect Hi-C contact matrices in cooler format
- Visualize contact matrices and identify TADs visually
- Compute the P(s) contact decay curve for quality assessment
- Detect A/B compartments by eigenvector decomposition
- Calculate insulation scores for TAD boundary calling
- Build aggregate pileup plots for weak signal detection
Tools covered: cooler, cooltools, numpy, pandas, matplotlib
Complicated moments explained
[Description truncada. Veja o README completo no GitHub.]