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bio-crispr-screens-screen-qc

Quality control for pooled CRISPR screens covering library representation, Gini index, log-skew, replicate Pearson and Spearman concordance, essentialome precision-recall AUC against CEGv2 (Hart 2017), Cas9 cut-toxicity diagnostics, copy-number amplicon detection (Aguirre 2016 / Munoz 2016), bottleneck propagation through plasmid pool, infection, selection, and endpoint stages, MOI verification, a

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Atualizado há 4 meses

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Version Compatibility

Reference examples tested with: MAGeCK 0.5+ (count + VISPR), MAGeCKFlute 2.0+ (R), pandas 2.2+, numpy 1.26+, scikit-learn 1.4+, matplotlib 3.8+, seaborn 0.13+.

Before using code patterns, verify installed versions match. If versions differ:

  • Python: pip show mageck then mageck count --help; pip show mageckflute
  • R: packageVersion('MAGeCKFlute') then ?BatchRemove / ?FluteRRA

If code throws ImportError, AttributeError, or TypeError, introspect the installe

[Description truncada. Veja o README completo no GitHub.]

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