Use omicverse's pyComBat wrapper to remove batch effects from merged bulk RNA-seq or microarray cohorts, export corrected matrices, and benchmark pre/post correction visualisations.
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Bulk RNA-seq batch correction with ComBat
Overview
Apply this skill when a user has multiple bulk expression matrices measured across different batches and needs to harmonise them before downstream analysis. It follows [t_bulk_combat.ipynb](../../omicverse_guide/docs/Tutorials-bulk/t_bulk_combat.ipynb), w hich demonstrates the pyComBat workflow on ovarian cancer microarray cohorts.
Instructions
Import core libraries
Load omicverse as ov, anndata, pandas as pd, and
[Description truncada. Veja o README completo no GitHub.]