dna-methylation
Bisulfite sequencing analysis: WGBS/RRBS processing, DMR calling, and epigenetic clock estimation.
Quick Reference
| Step | Tool | Notes | |------|------|-------| | Genome prep | bismark_genome_preparation | Creates CT/GA converted index | | Alignment | bismark | Bowtie2 backend | | Deduplication | deduplicate_bismark | Remove PCR duplicates | | Extraction | bismark_methylation_extractor | CpG/CHH/CHG contexts | | Load in R | methylKit::methRead() | From bismark
[Description truncada. Veja o README completo no GitHub.]