metabolomics
LC-MS metabolomics preprocessing, metabolite identification, and pathway enrichment analysis.
Quick Reference
| Step | Tool | Notes | |------|------|-------| | Peak picking | XCMS / MZmine | centWave algorithm for LC-MS | | Normalization | PQN, IS-based | Probabilistic Quotient Normalization | | Exact mass match | HMDB / KEGG | ± 5 ppm tolerance | | MS/MS matching | GNPS / MassBank | Cosine similarity threshold > 0.7 | | Structure prediction | SIRIUS + CSI:FingerID | De novo
[Description truncada. Veja o README completo no GitHub.]