nta-particle-tracker

NTA Particle Tracker

Purpose

The NTA Particle Tracker skill provides single-particle tracking analysis for nanoparticle size and concentration measurements, offering particle-by-particle characterization through direct visualization.

Capabilities

• Single-particle tracking
• Size-concentration profiles
• Fluorescence NTA mode
• Real-time size distribution
• Particle count and concentration
• Sample heterogeneity assessment

Usage Guidelines

NTA Measurement

1. Sample Preparation
2. Dilute to 10^7-10^9 particles/mL
3. Avoid air bubbles
4. Use appropriate buffer

1. Acquisition
2. Optimize camera level
3. Set detection threshold
4. Record multiple videos

1. Analysis
2. Track minimum 1000 particles
3. Set minimum track length
4. Generate size-concentration plot

Process Integration

• Statistical Particle Size Distribution Analysis
• Nanoparticle Drug Delivery System Development

Input Schema

{
  "sample_id": "string",
  "mode": "scatter|fluorescence",
  "dilution_factor": "number",
  "capture_time": "number (seconds)",
  "number_of_captures": "number"
}

Output Schema

{
  "concentration": "number (particles/mL)",
  "mean_size": "number (nm)",
  "mode_size": "number (nm)",
  "d10": "number (nm)",
  "d50": "number (nm)",
  "d90": "number (nm)",
  "size_distribution": {"sizes": [], "counts": []},
  "particles_tracked": "number"
}