Dados e Análise

SQL query optimization and database performance specialist. Use when

Use when doing ANY task involving Supabase. Triggers: Supabase products (Database, Auth, Edge Functions, Realtime, Storage, Vectors, Cron, Queues); client libraries and SSR integrations (supabase-js, @supabase/ssr) in Next.js, React, SvelteKit, Astro, Remix; auth issues (login, logout, sessions, JWT, cookies, getSession, getUser, getClaims, RLS); Supabase CLI or MCP server; schema changes, migrati

Single-cell RNA-seq analysis. Load .h5ad/10X data, QC, normalization, PCA/UMAP/t-SNE, Leiden clustering, marker genes, cell type annotation, trajectory, for scRNA-seq analysis.

Queries PharmGKB / CPIC / DPWG for drug-gene interactions; calls CYP2D6/CYP2C9/CYP2C19/DPYD/TPMT/NUDT15/UGT1A1/SLCO1B1 star alleles and phenotype with PharmCAT, Cyrius (CYP2D6 structural variants), Aldy, Stargazer; applies Caudle 2020 activity-score translation. Use when implementing pharmacogenomic-guided prescribing, applying CPIC vs DPWG guidance, screening HLA risk alleles for ICI / antiepilep

Generate, edit, and restore images with Google's Nano Banana (Gemini image models). Use whenever the user asks to "generate an image", "create an icon/favicon/logo", "edit this photo", "restore an old photo", "make a pattern/texture/wallpaper", "draw a diagram/flowchart/architecture", or "tell a visual story" — even when they don't explicitly say Nano Banana or Gemini. Always prefer this skill ove

Augments Trailmark code graphs with external audit findings from SARIF static analysis results and weAudit annotation files. Maps findings to graph nodes by file and line overlap, creates severity-based subgraphs, and enables cross-referencing findings with pre-analysis data (blast radius, taint, etc.). Use when projecting SARIF results onto a code graph, overlaying weAudit annotations, cross-refe

Use this skill for processing and analyzing large tabular datasets (billions of rows) that exceed available RAM. Vaex excels at out-of-core DataFrame operations, lazy evaluation, fast aggregations, efficient visualization of big data, and machine learning on large datasets. Apply when users need to work with large CSV/HDF5/Arrow/Parquet files, perform fast statistics on massive datasets, create vi

Detect and report drift between database schema and code data models. Works with SQLAlchemy, Django ORM, Prisma, TypeORM, and other ORMs. Generic across any project.

Add, configure, bind data to, and bulk-manage visuals on Power BI PBIR report pages using pbi-cli. Invoke this skill whenever the user mentions "add a chart", "bar chart", "line chart", "card", "KPI", "gauge", "scatter", "table visual", "matrix", "slicer", "combo chart", "bind data", "visual type", "visual layout", "resize visuals", "bulk update visuals", "bulk delete", "visual calculations", or w

Domine a análise de negócios moderna com análises impulsionadas por IA.

Query NCBI ClinVar via E-utilities for variant clinical significance, pathogenicity, disease associations. Search by gene/rsID/condition/review status; returns ClinSig, submitter data, conditions, HGVS. For GWAS use gwas-database; for variant consequence prediction use Ensembl VEP.

Analyze Perturb-seq and CROP-seq CRISPR screening data integrated with scRNA-seq. Use when identifying gene function through pooled genetic perturbations in single cells.