Design e Frontend

Map N6-methyladenosine (m6A) RNA modifications at single-nucleotide resolution using miCLIP (Linder 2015), miCLIP2 + m6Aboost machine learning (Kortel 2021), GLORI (Liu 2023, antibody-free chemical conversion), DART-seq (Meyer 2019, APOBEC1-YTH fusion), m6Anet (nanopore direct RNA), or MeRIP-seq with calibration. Use when distinguishing antibody-based from antibody-free m6A detection methods, appl

Use when receiving code review feedback, before implementing suggestions, especially if feedback seems unclear or technically questionable - requires technical rigor and verification, not performative agreement or blind implementation

Model Context Protocol (MCP) server patterns for building integrations with Claude Code. Triggers on: mcp server, model context protocol, tool handler, mcp resource, mcp tool.

Upgrade React applications to latest versions, migrate from class components to hooks, and adopt concurrent features. Use when modernizing React codebases, migrating to React Hooks, or upgrading to latest React versions.

When the user needs to decide what to build, cut, and defer for a first release or minimum viable version of a product or feature.

Design and implement event stores for event-sourced systems. Use when building event sourcing infrastructure, choosing event store technologies, or implementing event persistence patterns.

Use when auditing Claude skills and commands for quality. Supports Quick Scan (changed skills only) and Full Stocktake modes with sequential subagent batch evaluation.

Use when building or modifying user-facing interfaces. Use when creating components, implementing layouts, managing state, or when the output needs to look and feel production-quality rather than AI-generated.

Top 1% development standard for OC Pipeline and federal-grade construction software. Use when Bill asks to build features, fix bugs, write code, create components, or do any software development work. Activates for requests involving Supabase, Vercel, React, Node.js, database work, API development, or any coding tasks for OC Pipeline or related projects.

Gera modelos AIS.chat prontos para copiar e colar para o chatbot de IA escolar, abrangendo cenários de aprendizagem, parceiros de diálogo e assistentes. Use esta skill para criar, otimizar ou revisar modelos AIS.chat, mesmo com solicitações indiretas.

Complete browser automation with Playwright. Auto-detects dev servers, writes clean test scripts to /tmp. Test pages, fill forms, take screenshots, check responsive design, validate UX, test login flows, check links, automate any browser task. Use when user wants to test websites, automate browser interactions, validate web functionality, or perform any browser-based testing.

Hreflang and international SEO audit, validation, and generation. Detects common mistakes, validates language/region codes, and generates correct hreflang implementations. Use when user says "hreflang", "i18n SEO", "international SEO", "multi-language", "multi-region", or "language tags".