DevOps e Infra

Medicinal chemistry filters. Apply drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, complexity metrics, for compound prioritization and library filtering.

SOLID principles for Laravel 13 and PHP 8.3+. Files < 100 lines, interfaces separated, PHPDoc mandatory. Auto-detects Laravel and FuseCore architecture.

Use when starting any conversation - establishes mandatory workflows for finding and using skills, including using Skill tool before announcing usage, following brainstorming before coding, and creating TodoWrite todos for checklists

Ship workflow: detect + merge base branch, run tests, review diff, bump VERSION, update CHANGELOG, commit, push, create PR. Use when asked to "ship", "deploy", "push to main", "create a PR", or "merge and push". Proactively suggest when the user says code is ready or asks about deploying. Supports official (→ main) and beta (→ dev/develop) ship modes with auto-detection.

SOLID principles for Python 3.12+. Files < 100 lines, interfaces separated, modular architecture. Modules MANDATORY.

Search for raw byte patterns (hex sequences, opcodes) in binary code. Use when looking for specific instruction sequences, machine code patterns, UEFI SMI handlers, or known vulnerability signatures by their byte representation.

Aplica princípios SOLID a projetos genéricos em TypeScript, Bun e Node.js, com arquivos abaixo de 100 linhas, interfaces separadas e JSDoc obrigatório. Ideal para ferramentas CLI, bibliotecas, scripts, hooks e código TypeScript sem framework.

Use when facing 3+ independent failures that can be investigated without shared state or dependencies - dispatches multiple Claude agents to investigate and fix independent problems concurrently

This skill provides comprehensive automation for GitHub repository setup and configuration. It should be used when creating new projects, setting up CI/CD pipelines, configuring issue templates, enabling security scanning, or migrating existing projects to GitHub automation. The skill prevents 18 documented errors in GitHub Actions YAML syntax, workflow configuration, issue template structure, Dep

Python performance optimization patterns using profiling, algorithmic improvements, and acceleration techniques. Use when optimizing slow Python code, reducing memory usage, or improving application throughput and latency.

Use when auditing or generating hreflang for i18n SEO. Covers HTML link tags, HTTP headers, XML sitemap hreflang, self-referencing, return tags, x-default, ISO 639-1 + ISO 3166-1 code validation.

Use this skill when building Model Context Protocol (MCP) servers on Cloudflare Workers. This skill should be used when deploying remote MCP servers with TypeScript, implementing OAuth authentication (GitHub, Google, Azure, etc.), using Durable Objects for stateful MCP servers, implementing WebSocket hibernation for cost optimization, or configuring dual transport methods (SSE + Streamable HTTP).