Explorar skills

Use when working with context management context save

Understand what context is, why it matters, and the anatomy of context in agent systems

Variant calling with GATK HaplotypeCaller following best practices. Covers germline SNP/indel calling, GVCF workflow for cohorts, joint genotyping, and variant quality score recalibration (VQSR). Use when calling variants with GATK HaplotypeCaller.

恢复之前保存的会话上下文。列出所有待处理的 session，读取选定 session 的任务信息，更新进度，任务全部完成后删除文件。

Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin. Extracts nucleosome positioning patterns, fragment ratios, and DELFI-style fragmentation profiles for cancer detection. Use when leveraging fragment patterns for tumor detection or tissue-of-origin analysis.

Variant calling with GATK HaplotypeCaller following best practices. Covers germline SNP/indel calling, GVCF workflow for cohorts, joint genotyping, and variant quality score recalibration (VQSR). Use when calling variants with GATK HaplotypeCaller.

Apply compaction, masking, and caching strategies

Context management tools for Claude Code - provides intelligent codebase mapping with Python, Rust, and C++ parsing, duplicate detection, and MCP-powered symbol queries. Use this skill when working with large codebases that need automated indexing and context management.

Predicts potential off-target sites for a given sgRNA sequence using mismatch analysis.

Detect contamination and assess genome quality using CheckM, CheckM2, GTDB-Tk, and GUNC for metagenome-assembled genomes and isolate assemblies. Use when checking assemblies for contamination.

Strategies for managing LLM context windows including summarization, trimming, routing, and avoiding context rot Use when: context window, token limit, context management, context engineering, long context.

Automatically fetch latest library/framework documentation for Claude Code via Context7 API