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Atheris is a coverage-guided Python fuzzer based on libFuzzer. Use for fuzzing pure Python code and Python C extensions.

Guide for using uv - an extremely fast Python package and project manager written in Rust. Use when installing Python, managing virtual environments, adding dependencies, running scripts, building packages, or working with pyproject.toml. Replaces pip, pip-tools, pipx, poetry, pyenv, twine, and virtualenv.

Read and write compressed sequence files (gzip, bzip2, BGZF) using Biopython. Use when working with .gz or .bz2 sequence files. Use BGZF for indexable compressed files.

Build high-quality MCP servers with strong tool design, structured outputs, clear error handling, and realistic evaluations. Use when creating or improving MCP servers in TypeScript or Python for external APIs, services, or internal platforms.

Padrões especializados para desenvolvimento de Azure Functions, cobrindo o modelo de worker isolado, orquestração com Durable Functions, otimização de cold start e padrões de produção. Suporta modelos de programação .NET, Python e Node.js.

Docker standards — multi-stage builds, per-language base defaults (distroless Go, slim Python/Node), BuildKit cache mounts, non-root, multi-arch amd64+arm64, digest-pinned bases, Trivy scanning, Compose v2. Use when writing or reviewing Dockerfiles or Compose files.

Implement comprehensive testing strategies with pytest, fixtures, mocking, and test-driven development. Use when writing Python tests, setting up test suites, or implementing testing best practices.

SDK do Azure Queue Storage para Python, usado para enfileiramento de mensagens confiável, distribuição de tarefas e processamento assíncrono.

ENA REST API for sequences, reads, assemblies, and annotations. Portal API search, Browser API retrieval (XML/FASTA/EMBL), file reports for FASTQ/BAM URLs, taxonomy, cross-refs. For multi-DB Python use bioservices; for NCBI-only use pubmed-database or Biopython Entrez.

Python 3.14 enterprise standards — modern typing (PEP 649), immutable dataclasses, Protocol-based DI, asyncio discipline, pytest 9, psycopg + .sql files via importlib.resources. Use when writing, reviewing, or scaffolding Python code.

Convert laboratory instrument output files (PDF, CSV, Excel, TXT) to Allotrope Simple Model (ASM) JSON format or flattened 2D CSV. Use this skill when scientists need to standardize instrument data for LIMS systems, data lakes, or downstream analysis. Supports auto-detection of instrument types. Outputs include full ASM JSON, flattened CSV for easy import, and exportable Python code for data engin

Draw and export phylogenetic trees using Biopython Bio.Phylo with matplotlib and modern alternatives. Use when creating tree figures, customizing colors and labels, exporting to image formats, or choosing between Bio.Phylo, ggtree, ETE4, and iTOL for publication.