Explorar skills

Use when the user is doing AI/ML work in a scientific domain such as biology, chemistry, physics, astronomy, climate, genomics, materials, medicine, ecology, energy, engineering, math, drug discovery, protein design, weather modeling, theorem proving, single-cell, or PDE solving. Hugging Science is a curated catalog of scientific datasets, models, blog posts, and interactive Spaces. This skill hel

Use when completing public SpawnXchange direct purchases through /api/v1/items/{uuid}/acquire, verifying artifact delivery, and maintaining buyer state via the included references.

REST API design patterns including resource naming, status codes, pagination, filtering, error responses, versioning, and rate limiting for production APIs.

When the user wants to write an email to an investor — cold outreach, warm intro request, follow-up after a meeting, monthly investor update, or thank-you note. Also activates for "intro email", "investor email", "follow up with VC", or "investor update".

Calculates tumor mutational burden from WES/WGS/panel data with Friends of Cancer Research harmonization equations, per-assay calibration (FDA 10/Mb = 7.8 TSO500 = 8.4 OncomineTML), synonymous/indel/germline filtering, hypermutator tiering, blood TMB, and integration with HLA-LOH and neoantigen quality (Luksza 2017 fitness). Use when assessing ICI eligibility under tumor-specific cutoffs (McGrail

Calls m6A peaks from MeRIP-seq / m6A-seq paired IP-vs-input data using exomePeak2 (transcript-aware, GC-bias-corrected Poisson GLM; Liu 2022 *NAR Genom Bioinform* 4:lqac046), MeTPeak (HMM over sliding windows; Cui 2016 *Bioinformatics* 32:i378), MACS3 / MACS2 with --nomodel --broad --keep-dup all (genome-wide broad alternative), and DRACH motif enrichment confirmation via HOMER or ggseqlogo as a s

Atualiza o context-mode do GitHub e corrige hooks/configurações. Baixa a versão mais recente, compila, instala, atualiza o npm global e configura os hooks. Gatilho: /context-mode:ctx-upgrade

Generate images, videos, speech audio, and music using the PonyFlash Python SDK. Also handle local media editing with FFmpeg, including clip, concat, transcode, extract audio, frame capture, subtitle capability checks, and ASS subtitle prep. Use when the user asks to create, generate, produce, edit, trim, merge, concatenate, transcode, subtitle, or render AI-generated media content.

Structured manuscript/grant review with checklist-based evaluation. Use when writing formal peer reviews with specific criteria methodology assessment, statistical validity, reporting standards compliance (CONSORT/STROBE), and constructive feedback. Best for actual review writing, manuscript revision. For evaluating claims/evidence quality use scientific-critical-thinking; for quantitative scoring

Extracts and analyzes competitors' ads from ad libraries (Facebook, LinkedIn, etc.) to understand what messaging, problems, and creative approaches are working. Helps inspire and improve your own ad campaigns.

Taxonomic classification of ASVs using reference databases like SILVA, GTDB, or UNITE. Covers naive Bayes classifiers (DADA2, IDTAXA) and exact matching approaches. Use when assigning taxonomy to ASVs after DADA2 amplicon processing.

Unified social media skill — create, adapt, distribute, and schedule content across LinkedIn, Twitter/X, Instagram, TikTok, YouTube, Threads, Bluesky, Facebook, and newsletters. Covers platform-native content creation, cross-platform distribution (never identical cross-posts), content calendars, repurposing systems, engagement strategy, and analytics. Use when the user mentions 'LinkedIn post,' 'T