Explorar skills

Build comprehensive chromatin accessibility maps by aggregating ATAC-seq and DNase-seq narrowPeak data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is chromatin accessible in my tissue?" by combining peak calls into a union peak set. Handles cross-lab variation, ATAC vs DNase platform differences, and ENCODE blocklist filtering.

Discover and characterize regulatory elements (enhancers, promoters, silencers, insulators, super-enhancers) using ENCODE data and the cCRE catalog. Use when the user wants to find candidate regulatory elements, identify active enhancers in a tissue, map promoter states, classify chromatin states with ChromHMM, identify super-enhancers with ROSE, understand the functional validation hierarchy (CRI

Find and work with ENCODE single-cell genomics data including scRNA-seq and scATAC-seq. Use when the user asks about single-cell experiments, cell type resolution, clustering from ENCODE data, deconvolution of bulk signals using single-cell references, or comparing single-cell vs bulk profiles. Covers platform differences (10X Chromium, Smart-seq2, Drop-seq), quality limitations of single-cell dat

Guide for integrating GTEx tissue expression data with ENCODE regulatory elements. Use when users need to check if a gene is expressed in a tissue, correlate regulatory elements with expression, or validate ENCODE findings against GTEx. Trigger on: GTEx, tissue expression, gene expression levels, expression atlas, eQTL, tissue-specific expression, TPM values.

Execute ENCODE ChIP-seq processing pipeline from FASTQ to peaks and signal tracks. Child of pipeline-guide. Provides stage-by-stage Nextflow execution with Docker containers and cloud deployment. Use when users need to process ChIP-seq data following ENCODE standards, run peak calling with MACS2, perform IDR analysis, or generate signal tracks. Trigger on: ChIP-seq pipeline, run ChIP-seq, process

Build comprehensive histone mark maps by aggregating narrowPeak data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is this histone mark present in my tissue?" by combining peak calls from multiple studies into a union peak set with confidence annotations. Handles cross-lab batch effects, broad vs narrow marks, and ENCODE blocklist filtering.

Build WooCommerce admin interfaces — settings pages, admin menus, product data tabs/panels, order meta boxes, WooCommerce Admin (React analytics), and reports. Use when creating admin-facing configuration or display pages.

Build Node.js backends for Salesforce Commerce — SFCC server-side JavaScript (not actual Node.js runtime), PWA Kit backend (Express-like SSR server), Commerce SDK for server-side SCAPI access, and async patterns for external service integration. Use when building server-side commerce logic.

Implement Magento 2 security — CSP, 2FA, CSRF protection, ACL, admin security configuration, input validation, and security best practices. Use when hardening a Magento installation or reviewing security posture.

Test WebMCP tools with AI agents — Chrome DevTools integration, agent testing workflows, tool discovery verification, and end-to-end commerce flow testing. Use when validating that tools work correctly with real AI agents.

Manage Shopify catalog — Product, Variant, and Option models, collections, metafields and metaobjects, inventory management, product taxonomy, bulk operations, and media. Use when working with Shopify product data.

Converts Elementor-built WordPress pages to native Gutenberg blocks. Reads Elementor's JSON widget tree from post meta, maps each widget to its closest core block equivalent, generates a migration plan for approval, and writes clean block markup to the target pages. Use when user says "migrate Elementor to Gutenberg", "drop Elementor", "switch to native blocks", or "rebuild Elementor pages in the