Explorar skills

Set up the ENCODE Toolkit server connection. Use when the user needs help installing, configuring, or troubleshooting the ENCODE connector.

Web research via platform web tools. Use for technical comparisons,

Execute ENCODE Whole Genome Bisulfite Sequencing (WGBS) pipeline from FASTQ to methylation calls. Child of pipeline-guide. Provides Nextflow execution with Docker and cloud deployment. Use when processing WGBS/bisulfite-seq data, calling methylation levels, generating bedMethyl files. Trigger on: WGBS pipeline, bisulfite sequencing, methylation calling, DNA methylation pipeline, bismark, bwa-meth,

Run Claude Code in autonomous iteration loops until task completion — PRD-based feature development, test coverage improvement, lint fixing, documentation generation, dataset creation, or framework migrations. Uses in-session loop mechanism with specialized templates. Triggers on autonomous loop, iterate until done, run until passing, keep going until, ralph, PRD execution.

This skill should be used when creating, auditing, or maintaining AGENTS.md files and Codex CLI configuration for any project—including initializing AGENTS.md for cross-agent compatibility (Codex, Cursor, Copilot, Devin, Jules, Amp, Gemini CLI), generating config.toml or .rules files, scaffolding .agents/skills/, converting CLAUDE.md to AGENTS.md, or auditing existing agent configs for bloat and s

Use to evaluate a service or feature against Downe's 15 principles of good services.

Synchronize canvas state across team sessions via git. Ensures all team members see the same product knowledge.

Intercept, inspect, and modify HTTP/HTTPS traffic via a Rust MITM proxy with Lua scripting hooks. Supports API debugging, LLM call capture for evals, endpoint mocking, CORS/auth header injection, latency simulation, and telemetry blocking. Triggers on 'proxy', 'intercept traffic', 'inspect requests', 'mock API', 'capture API calls', 'MITM', 'network debug', 'HTTP inspection'.

Create normal git commits with logical grouping. Use when committing, saving changes, creating commits, or grouping work into commits. NOT for amending, rebasing, force-pushing, or rewriting history.

Use to prioritize solutions or opportunities using ICE scoring with evidence-backed confidence.

Build complete userModels for people Claudicle collaborates with. Creates core persona files, social dossiers with voice analysis, content archives, and INDEX registration. Use when asked to create a user model, build a persona, or document someone's voice and identity.

Build comprehensive DNA methylation maps by aggregating WGBS (Whole Genome Bisulfite Sequencing) data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is DNA methylated/unmethylated in my tissue?" by combining per-CpG methylation data into tissue-level methylation profiles. Handles coverage filtering, identifies hypomethylated regions (HMRs) and partia