Explorar skills

Bulk RNA-seq DE with PyDESeq2: load counts, normalize, fit negative binomial models, Wald test (BH-FDR), LFC shrinkage, volcano/MA plots. Use for two-group comparisons, multi-factor designs with batch correction, multiple contrasts.

Python statistical modeling: regression (OLS, WLS, GLM), discrete (Logit, Poisson, NegBin), time series (ARIMA, SARIMAX, VAR), with rigorous inference, diagnostics, and hypothesis tests. Use scikit-learn for ML; statistical-analysis for test choice.

LLM-driven hypothesis generation/testing on tabular data. Three methods: HypoGeniC (data-driven), HypoRefine (literature+data), Union. Iterative refinement, Redis caching, multi-hypothesis inference. Manual: hypothesis-generation; ideation: scientific-brainstorming.

Use when planning to rank for a specific keyword. The agent Googles it, reads the top 10, classifies intent, reads the top 3 competitor pages, and produces a 90-day ranking plan with intent, SERP analysis, and content recommendations.

Use when auditing a specific page's SEO performance, content quality, and competitive position. The agent fetches the URL, Googles the primary keyword, reads the top 3 competitors, and produces a full 7-dimension audit — no exports, no analytics access required.

Use when planning a new article. The agent Googles the keyword, reads the top 10 results, classifies intent, maps the content gap, and produces a writer-ready brief with structure, outline, and on-page artifacts. No keyword tool required.

Use when writing a complete SEO article. Includes the full anti-AI-slop ruleset (banned vocabulary, banned phrases, banned structural patterns) and voice rules. The agent researches the SERP itself if needed — no keyword data exports required.

Use when planning a topic cluster (hub + spokes) for a new content area. The agent researches the space, identifies the hub topic, maps the spokes, and produces a specific content plan with internal linking strategy.

Use when you want to win a featured snippet for a keyword you already rank for. The agent checks the current snippet format, analyzes your content, and rewrites the relevant section to match what Google wants.

Use when rewriting or refreshing an existing page that's underperforming. The agent fetches the URL, analyzes the current content, researches the SERP, and rewrites using the full anti-AI-slop ruleset — no data exports needed.

Use when auditing a page for E-E-A-T signals. The agent reads the page and scores Experience, Expertise, Authoritativeness, and Trustworthiness — then tells you exactly what to add to each dimension.

Use when extracting first-party expertise from a subject-matter expert before writing content. Produces a knowledge document of contrarian takes, specific examples, and surprising outcomes that AI can't fabricate.