Explorar skills

Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research and patient matching.

Cheminformatics toolkit for fine-grained molecular control. SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure search, 2D/3D generation, similarity, reactions. For standard workflows with simpler interface, use datamol (wrapper around RDKit). Use rdkit for advanced control, custom sanitization, specialized algorithms.

Create distinctive, production-grade frontend interfaces with high design quality. Use this skill when the user asks to build web components, pages, or applications. Generates creative, polished code that avoids generic AI aesthetics.

Automated hypothesis generation and testing using large language models. Use this skill when generating scientific hypotheses from datasets, combining literature insights with empirical data, testing hypotheses against observational data, or conducting systematic hypothesis exploration for research discovery in domains like deception detection, AI content detection, mental health analysis, or othe

Design durable workflows with Temporal for distributed systems. Covers workflow vs activity separation, saga patterns, state management, and determinism constraints. Use when building long-running processes, distributed transactions, or microservice orchestration.

AI-assisted pair programming with multiple modes (driver/navigator/switch), real-time verification, quality monitoring, and comprehensive testing. Supports TDD, debugging, refactoring, and learning sessions. Features automatic role switching, continuous code review, security scanning, and performance optimization with truth-score verification.

Automated coordination, formatting, and learning from Claude Code operations using intelligent hooks with MCP integration. Includes pre/post task hooks, session management, Git integration, memory coordination, and neural pattern training for enhanced development workflows.

Deep learning framework (PyTorch Lightning). Organize PyTorch code into LightningModules, configure Trainers for multi-GPU/TPU, implement data pipelines, callbacks, logging (W&B, TensorBoard), distributed training (DDP, FSDP, DeepSpeed), for scalable neural network training.

Autonomous biomedical AI agent framework for executing complex research tasks across genomics, drug discovery, molecular biology, and clinical analysis. Use this skill when conducting multi-step biomedical research including CRISPR screening design, single-cell RNA-seq analysis, ADMET prediction, GWAS interpretation, rare disease diagnosis, or lab protocol optimization. Leverages LLM reasoning wit

Build Shopify applications, extensions, and themes using GraphQL/REST APIs, Shopify CLI, Polaris UI components, and Liquid templating. Capabilities include app development with OAuth authentication, checkout UI extensions for customizing checkout flow, admin UI extensions for dashboard integration, POS extensions for retail, theme development with Liquid, webhook management, billing API integratio

Use when design is complete and you need detailed implementation tasks for engineers with zero codebase context - creates comprehensive implementation plans with exact file paths, complete code examples, and verification steps assuming engineer has minimal domain knowledge

Transform brain dumps into polished blog posts in Nick Nisi's voice. Use when the user wants to write a blog post with scattered ideas, talking points, and conclusions that need organization into a cohesive narrative with Nick's conversational, authentic, and thoughtful tone.