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Automate Zendesk tasks via Rube MCP (Composio): tickets, users, organizations, replies. Always search tools first for current schemas.

"End-to-end binder design using BindCraft hallucination. Use this skill when: (1) Designing protein binders with built-in AF2 validation, (2) Running production-quality binder campaigns, (3) Using different design protocols (fast, default, slow), (4) Need joint backbone and sequence optimization, (5) Want high experimental success rate.

Parses, queries, converts, and extracts from GTF and GFF3 gene-model annotation files - walking the gene/transcript/exon/CDS hierarchy with gffutils (queryable SQLite DB), converting formats and extracting transcript/CDS/protein FASTA with gffread, slurping to dataframes with gtfparse/pyranges, and sanitizing malformed files with AGAT. Covers the 1-based-inclusive vs 0-based BED coordinate convers

Develop PowerShell scripts, tools, modules, and GUIs following Microsoft best practices. Use when writing PowerShell code, creating Windows Forms/WPF interfaces, working with PowerShell Gallery modules, or needing cmdlet/module recommendations. Covers script development, parameter design, pipeline handling, error management, and GUI creation patterns. Verifies module availability and cmdlet syntax

Downloads videos from YouTube and other platforms for offline viewing, editing, or archival. Handles various formats and quality options.

Download, prepare, and manage reference panels for phasing and imputation. Covers 1000 Genomes, HRC, and TOPMed panels. Use when setting up imputation infrastructure or selecting appropriate reference panels for target populations.

Generate high-quality, minimalistic, and geometric SVG logos using Python scripts. Use this skill when users need to create logos, icons, or visual identities with geometric primitives (circles, rects, paths) and specific color schemes. Applies generative design principles with standardized workflows for scalable SVG output.

Run any model on RunComfy from the command line. The `runcomfy` CLI is one binary, one auth, hundreds of model endpoints — image generation, image edit, video generation, image-to-video, lip-sync, face swap, video edit, inpainting, outpainting, extend, ControlNet, relight, upscale, LoRA training and more. Submit a request, poll for status, download the output. This skill teaches the agent how to i

Identify enriched sequence motifs at CLIP-seq binding sites for RBP binding specificity. Use when characterizing the sequence preferences of an RNA-binding protein.

Systematic framework for extracting actionable items from documents and

Get current weather conditions for a location. Use this skill when users ask about weather, temperature, current conditions, forecasts, or any weather-related queries like "What's the weather?", "Is it raining?", "How hot is it outside?", "What's the temperature?", or "Should I bring an umbrella?". Supports automatic location detection via IP or specific location queries.

Automated SQL injection detection and exploitation tool for web application security testing. Use when: (1) Testing web applications for SQL injection vulnerabilities in authorized assessments, (2) Exploiting SQL injection flaws to demonstrate impact, (3) Extracting database information for security validation, (4) Bypassing authentication mechanisms through SQL injection, (5) Identifying vulnerab