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Alpha and beta diversity analysis for microbiome data. Calculate within-sample richness, evenness, and between-sample dissimilarity with phyloseq and vegan. Use when comparing community composition across samples or testing for group differences in microbiome structure.

Convert Pencil `.pen` design files and named Pencil node IDs into production frontend code. Use when asked to implement, migrate, reproduce, or refine a Pencil/Figma-like visual design in code, especially for responsive artboards, glassmorphism, typography matching, background image layers, design tokens, or visual fidelity debugging against Pencil node IDs.

Optimize Apache Spark jobs with partitioning, caching, shuffle optimization, and memory tuning. Use when improving Spark performance, debugging slow jobs, or scaling data processing pipelines.

Core Python library for astronomy and astrophysics workflows that need Astropy APIs, including units/quantities, coordinates, FITS I/O, tables, time systems, WCS, and cosmology. Use when implementing or debugging astronomical data analysis code with Astropy.

Prepare git commit messages following conventional commits. Activates on: commit, prepare commit, commit this, commit message, ready to commit, stage and commit

Submit and manage protocols on Ginkgo Bioworks Cloud Lab (cloud.ginkgo.bio), a web-based interface for autonomous lab execution on Reconfigurable Automation Carts (RACs). Use when the user wants to run cell-free protein expression (validation or optimization), generate fluorescent pixel art, or interact with Ginkgo Cloud Lab services. Covers protocol selection, input preparation, pricing, and orde

O Azure Maps SDK para .NET oferece serviços baseados em localização, incluindo geocodificação, roteamento, renderização, geolocalização e clima. Utilize-o para busca de endereços, direções, blocos de mapa, geolocalização por IP e dados meteorológicos.

Frontend development guidelines for React/TypeScript applications. Modern patterns including Suspense, lazy loading, useSuspenseQuery, file organization with features directory, MUI v7 styling, TanStack Router, performance optimization, and TypeScript best practices. Use when creating components, pages, features, fetching data, styling, routing, or working with frontend code.

Use when creating SQLModel database models, CRUD operations, queries with joins, or relationships. NOT when non-database operations, plain SQL, or unrelated data handling. Triggers: "SQLModel", "database model", "CRUD", "create/read/update/delete", "query", "ForeignKey", "relationship".

Efficient storage and retrieval of genomic variant data using TileDB. Scalable VCF/BCF ingestion, incremental sample addition, compressed storage, parallel queries, and export capabilities for population genomics.

Use when working with code refactoring context restore

Guide for implementing HolmesGPT - an AI agent for troubleshooting cloud-native environments. Use when investigating Kubernetes issues, analyzing alerts from Prometheus/AlertManager/PagerDuty, performing root cause analysis, configuring HolmesGPT installations (CLI/Helm/Docker), setting up AI providers (OpenAI/Anthropic/Azure), creating custom toolsets, or integrating with observability platforms