jackspace

Consulta PubChem (mais de 110 milhões de compostos) via API PUG-REST/PubChemPy. Permite buscar por nome/CID/SMILES, recuperar propriedades, e realizar buscas de similaridade/subestrutura e bioatividade para quimioinformática.

Access Human Metabolome Database (220K+ metabolites). Search by name/ID/structure, retrieve chemical properties, biomarker data, NMR/MS spectra, pathways, for metabolomics and identification.

Graph-based drug discovery toolkit. Molecular property prediction (ADMET), protein modeling, knowledge graph reasoning, molecular generation, retrosynthesis, GNNs (GIN, GAT, SchNet), 40+ datasets, for PyTorch-based ML on molecules, proteins, and biomedical graphs.

Query ChEMBL's bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.

Comprehensive Python library for astronomy and astrophysics. This skill should be used when working with astronomical data including celestial coordinates, physical units, FITS files, cosmological calculations, time systems, tables, world coordinate systems (WCS), and astronomical data analysis. Use when tasks involve coordinate transformations, unit conversions, FITS file manipulation, cosmologic

Generates comprehensive planning documentation for web application projects, structuring work into context-safe phases with built-in verification criteria. Creates IMPLEMENTATION_PHASES.md, DATABASE_SCHEMA.md, API_ENDPOINTS.md, ARCHITECTURE.md, and other planning docs based on project needs. Optimized for Cloudflare Workers + Vite + React stack. Use when starting new projects, adding major feature

Executes OpenAI Codex CLI for code analysis, refactoring, and automated editing. Activates when users mention codex commands, code review requests, or automated code transformations requiring advanced reasoning models.

This skill should be used when working with LaminDB, an open-source data framework for biology that makes data queryable, traceable, reproducible, and FAIR. Use when managing biological datasets (scRNA-seq, spatial, flow cytometry, etc.), tracking computational workflows, curating and validating data with biological ontologies, building data lakehouses, or ensuring data lineage and reproducibility

Access USPTO APIs for patent/trademark searches, examination history (PEDS), assignments, citations, office actions, TSDR, for IP analysis and prior art searches.

Comprehensive guide for Cloudflare Durable Objects - globally unique, stateful objects for coordination, real-time communication, and persistent state management. Use when: building real-time applications, creating WebSocket servers with hibernation, implementing chat rooms or multiplayer games, coordinating between multiple clients, managing per-user or per-room state, implementing rate limiting

Deep learning framework (PyTorch Lightning). Organize PyTorch code into LightningModules, configure Trainers for multi-GPU/TPU, implement data pipelines, callbacks, logging (W&B, TensorBoard), distributed training (DDP, FSDP, DeepSpeed), for scalable neural network training.

Frontend React hooks for AI-powered chat interfaces, completions, and streaming UIs with Vercel AI SDK v5. Includes useChat, useCompletion, and useObject hooks for building interactive AI applications. Use when: building React chat interfaces, implementing AI completions in UI, streaming AI responses to frontend, handling chat message state, building Next.js AI apps, managing file attachments with