Explore skills

HLA Typing identifies human leukocyte antigen alleles, crucial for antigen presentation and initiating immune responses.

Immune repertoire sequencing covers TRUST4/MiXCR workflows, diversity metrics, clonal tracking, Morisita-Horn overlap, VDJdb lookup, and CDR3 Hamming clustering.

Isoform analysis with long reads, featuring Minimap2 for splice alignment, bambu for isoform discovery, and DRIMSeq for differential isoform usage.

Performs CRISPR screen analysis using MAGeCK.

MOFA2 is an unsupervised multi-omics factor analysis for variance decomposition, factor interpretation, and shared/view-specific signal separation. Use it when integrating multiple omics layers.

Population genetics and molecular evolution, covering topics such as Hardy-Weinberg, Wright-Fisher drift, selection models, dN/dS, Tajima's D, Fst, and the neutral theory.

Graph Neural Networks for Molecular Property Prediction with RDKit.

Community detection in biological networks, utilizing Louvain/Leiden algorithms, modularity Q, WGCNA co-expression modules, and Cytoscape export.

Taxonomic profiling of shotgun metagenomes: host decontamination, Kraken2 classification, Bracken abundance re-estimation.

NGS platform comparison, FASTQ format, Phred quality scores, and QC metrics. Reference for sequencing technology selection and read quality assessment.

Implement Lagrange and Newton interpolation polynomials, explain the Runge phenomenon, and apply cubic spline interpolation to reconstruct missing time points in biological time series.

Viral phylodynamics: molecular clocks, root-to-tip regression, time-scaled phylogenies, Bayesian skyline plots, and phylogeography tool selection.