Dados e Análise

Query ChEMBL's bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.

Permanent capability skill for authenticated Instagram data extraction using instaloader and a reusable session cookie file

Handles BED-format genomic intervals (BED3 through BED12, narrowPeak/broadPeak) and the coordinate-system substrate the whole interval category rests on, with bedtools (CLI) and pybedtools/pyranges/pandas (Python). Covers the 0-based half-open vs 1-based-closed convention boundary and the start-1/end-unchanged conversion, the silent failures (chrom-name mismatch, CRLF, lexicographic-vs-version sor

Gerenciamento de banco de dados, formulários, relatórios e operações de dados com LibreOffice Base.

Create and manage production Grafana dashboards for real-time visualization of system and application metrics. Use when building monitoring dashboards, visualizing metrics, or creating operational observability interfaces.

Therapeutics Data Commons. AI-ready drug discovery datasets (ADME, toxicity, DTI), benchmarks, scaffold splits, molecular oracles, for therapeutic ML and pharmacological prediction.

Construa, atualize e resolva problemas de plugins AllayMC em Java ou outras linguagens JVM. Utilize ao criar um novo plugin AllayMC, migrar um plugin existente para uma nova versão da API Allay, configurar comandos/eventos/tarefas/configurações, ou configurar Gradle e metadados do plugin (plugin.json ou bloco de plugin AllayGradle).

Performance profiling — measures code execution time, DB call time, and identifies bottlenecks at both the application and database layer. Use when asked to "profile performance", "measure execution time", "find bottlenecks", "check response times", or "why is this slow".

Patterns for SQLite databases in Python projects - state management, caching, and async operations. Triggers on: sqlite, sqlite3, aiosqlite, local database, database schema, migration, wal mode.

Cheminformatics toolkit for fine-grained molecular control. SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure search, 2D/3D generation, similarity, reactions. For standard workflows with simpler interface, use datamol (wrapper around RDKit). Use rdkit for advanced control, custom sanitization, specialized algorithms.

Explore and understand the Empathy Ledger codebase architecture, data flows, database schema, services, and how components connect. Use when you need to understand where things are, how data flows, or how different parts of the system relate to each other.

Universal database operations skill for modern applications. Expert in SQLModel/SQLAlchemy patterns, async database operations, connection pooling, migrations, performance optimization, and multi-database support (PostgreSQL, MySQL, SQLite). Provides production-ready patterns for any database-driven application.