DevOps e Infra

Configure and manage development, staging, and production environments. Use when setting up environment variables, managing configurations, or separating environments. Handles .env files, config management, and environment-specific settings.

Performs gene-level association from GWAS summary statistics via genetically predicted tissue expression using FUSION, PrediXcan, S-PrediXcan, S-MultiXcan, UTMOST, MOSTWAS, kTWAS, EpiXcan, TIGAR-V2, and probabilistic fine-mapping with FOCUS and MA-FOCUS. Use when running TWAS from GWAS sumstats, prioritising candidate causal genes from a GWAS lead locus, picking single-tissue vs cross-tissue model

Set up Prometheus for comprehensive metric collection, storage, and monitoring of infrastructure and applications. Use when implementing metrics collection, setting up monitoring infrastructure, or configuring alerting systems.

Configure Istio traffic management including routing, load balancing, circuit breakers, and canary deployments. Use when implementing service mesh traffic policies, progressive delivery, or resilience patterns.

Network architecture, troubleshooting, and infrastructure patterns. Use

Manage and monitor UniFi sites across your account. View site details, organization structure, and multi-site overview for centralized infrastructure management.

Esta skill abrangente da plataforma Cloudflare cobre Workers, Pages, armazenamento (KV, D1, R2), IA, feature flags, redes, segurança e infraestrutura como código. É ideal para qualquer tarefa de desenvolvimento Cloudflare, priorizando a recuperação de informações da documentação oficial.

Computes and interprets sequencing read depth and coverage over a genome, windows, or target regions with mosdepth (windowed depth, cumulative distribution, --quantize callable BEDs), bedtools genomecov/coverage (bedGraph tracks, per-target stats), samtools depth/coverage (per-base depth, per-contig depth+breadth). Covers the breadth-vs-mean distinction, the cumulative-coverage curve, evenness (CV

SPARC (Specification, Pseudocode, Architecture, Refinement, Completion) comprehensive development methodology with multi-agent orchestration

· Review product, engineering, design, and business decisions with Jekyll/Hyde lenses. Triggers: 'jekyll', 'hyde', 'decision review', 'strategy review', 'red-team', 'dark pattern'.

Design multi-cloud architectures using a decision framework to select and integrate services across AWS, Azure, GCP, and OCI. Use when building multi-cloud systems, avoiding vendor lock-in, or leveraging best-of-breed services from multiple providers.

When the user asks about roadmap planning, sprint planning, milestone estimation, or capacity planning