Pesquisa e Web

Runs JACKS (Joint Analysis of CRISPR/Cas9 Knockout Screens; Allen et al 2019 Genome Research) which models per-sgRNA log-fold-change as the product of a treatment-dependent gene-essentiality term and a treatment-independent guide-efficacy term. Covers the Bayesian decomposition math, the hierarchical efficacy prior shared across screens performed with the same library, when JACKS outperforms MAGeC

Executive communication style for all-hands emails. Balances transparency with appropriate messaging.

Best practices and patterns for Next.js App Router, Server Actions, and Routing in this project.

Detect, date, and contextualize whole-genome duplication (WGD / paleopolyploidy) events using wgd v2 (Chen & Zwaenepoel 2024), KsRates (Sensalari 2022 substitution-rate-corrected Ks dating), DupGen_finder (Qiao 2019), MAPS (Li 2018 phylogenomic), POInT (Conant 2008 ordered-block), SLEDGe (2024 ML-based), Whale.jl (Bayesian DTL+WGD), and synteny-anchored paranome construction. Use when identifying

Control a Playwright browser via CLI - navigate, interact, and screenshot

Comprehensive framework for analyzing, creating, and refining prompts for AI systems using evidence-based techniques

飞书邮箱 — draft, compose, send, reply, forward, read, and search emails; manage drafts, folders, labels, contacts, and attachments. Use when user mentions 起草邮件, 写一封邮件, 拟邮件, 草稿, 发通知邮件, 发送邮件, 发邮件, 回复邮件, 转发邮件, 查看邮件, 看邮件, 读邮件, 搜索邮件, 查邮件, 收件箱, 邮件会话, 编辑草稿, 管理草稿, 下载附件, 邮件文件夹, 邮件标签, 邮件联系人, 监听新邮件, draft, compose, send email, reply, forward, inbox, mail thread.

全球最大的 Claude Code 技能聚合库 · 收录 3900+ 来自 12+ 来源的技能，提供在线搜索与趋势分析看板 / The world's largest Claude Code skill aggregation hub — 3900+ skills from 12+ sources with online search and trend dashboard

Biomedical OS Core & MCP Server

Automate Google Calendar events, scheduling, availability checks, and attendee management via Rube MCP (Composio). Create events, find free slots, manage attendees, and list calendars programmatically.

Operate as an agentic engineer using eval-first execution, decomposition, and cost-aware model routing.

Break a plan, spec, or PRD into independently-grabbable issues on the project issue tracker using tracer-bullet vertical slices. Use when user wants to convert a plan into issues, create implementation tickets, or break down work into issues.